Efficacy of low-dose nicardipine for emergent treatment of severe postpartum hypertension in maternal intensive care units: An observational study

Qi, Haifeng; Qin, Jiali; Ren, Li; Li, Lan; Lan, Lan; Yan, Yunsheng; Gan, Shengwen; Zhang, Yaozong

doi:10.1016/j.preghy.2020.04.012

Cited by 6 publications

(7 citation statements)

References 23 publications

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“…Hence, most patients are reluctant to do off-bed activities, and their prognostic recovery will be affected. Aiming at this situation, the nursing personnel should reasonably evaluate patients' condition and give corresponding guidance to enhance their awareness of self-care and confidence in recovery [ 12 – 14 ]. (5) In addition, offline and online pain care, diet guidance, hygiene care, breastfeeding nursing, etc., should be performed on patients after C-section to promote clinical nursing quality and postoperative recovery.…”

Section: Study Methodsmentioning

confidence: 99%

Effect of Comprehensive Nursing Intervention Under Internet-Based WeChat Platform Education on Postoperative Recovery of Puerperae Undergoing Cesarean Section

Kong

Liu

Jiang

2022

Journal of Healthcare Engineering

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Objective. To explore the effect of comprehensive nursing intervention under internet-based WeChat platform education on postoperative recovery of puerperae undergoing cesarean section (C-section). Methods. A total of 96 patients undergoing C-section in our hospital from June 2018 to October 2021 were selected for the retrospective analysis and grouped according to the nursing intervention modes as follows: patients who received a routine nursing intervention were included in the control group, and patients who received comprehensive nursing intervention under internet-based WeChat platform education were included in the study group, with 48 cases each. After the intervention, the postoperative recovery of puerperae undergoing C-section and obstetrics nursing quality were scientifically assessed. Results. No statistical differences in general data between the two groups were observed ( P > 0.05 ). Compared with the control group, patients in the study group had obviously earlier initial time of lactation ( P < 0.05 ), significantly higher breast milk amount within 48 h after delivery ( P < 0.05 ), significantly earlier spontaneous urination time, anal exhaust time and off-bed activity time ( P < 0.05 ), obviously better mastery of health knowledge ( P < 0.05 ), and, in terms of SCL-90, remarkably lower total score, average total positive score, and the number of positive items and scores in dimensions, such as somatization, obsessive-compulsive, depression, anxiety, interpersonal sensibility, anger-hostility, phobic-anxiety, and paranoid ideation ( P < 0.05 ). At discharge, 3 months, and 6 months of follow-up, patients in the study group obtained significantly higher scores on quality of life than the control group ( P < 0.05 ). Conclusion. In the nursing of puerperae undergoing C-section, comprehensive nursing intervention measures based on the internet-based WeChat platform education can effectively improve the early lactation, mastery of health knowledge, and adverse emotions of puerpera and promote their postoperative recovery.

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Section: Study Methodsmentioning

confidence: 99%

Effect of Comprehensive Nursing Intervention Under Internet-Based WeChat Platform Education on Postoperative Recovery of Puerperae Undergoing Cesarean Section

Kong

Liu

Jiang

2022

Journal of Healthcare Engineering

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“…Tachycardia was defined as a heart rate > 100 beats per minute (bpm), and bradycardia as a heart rate < 60 bpm. Postpartum hemorrhage was denoted as a post-delivery blood loss > 500 mL [4].…”

Section: Discussionmentioning

confidence: 99%

“…Nicardipine (Astellas Pharmaceutical Co., Ltd, Shenyang, China) was delivered through a continuous-infusion pump, with details described previously [4]. Briefly, the initial dosage of nicardipine was 2 mg/hour for the patients with an SBP 160-179 mm Hg and 4 mg/hour for those with an SBP ≥ 180 mm Hg.…”

Section: Drug Treatmentmentioning

confidence: 99%

“…Nicardipine is a dihydropyridine-type calcium-channel blocker that provides effective treatment in patients with hypertension during pregnancy. Previous studies have reported a safe and rapid effect of intravenous infusion of nicardipine in patients with severe peripartum hypertension [4,5]. As sequential therapy, oral medications should be administrated after an elevated blood pressure has been brought to and is maintained at a satisfactory level.…”

Section: Introductionmentioning

confidence: 99%

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Effects of intravenous nicardipine followed by oral labetalol in combination with nifedipine controlled-release tablet on severe peripartum hypertension

Lan,

Yan,

et al. 2024

Ginekol Pol

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“…Nicardipine, a commonly used antihypertensive medication, is a potent vasodilator, which acts as a calcium channel blocker (CCB) on the vascular smooth muscle wall. [13][14][15] Nicardipine selectively responds to coronary and cerebral vessels over the systemic circulation, resulting in increased cerebral blood flow and oxygen delivery, with less inotropic effects on the myocardium. [16,17] Thus, nicardipine has been used widely for managing acute severe hypertension in patients with cerebrovascular accidents and postoperative BP control after cardiac or neurovascular surgery.…”

Section: Introductionmentioning

confidence: 99%

Use of continuous infusion of nicardipine to control persistent postpartum hypertension: A retrospective study

et al. 2022

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To evaluate the effect of continuous infusion of nicardipine on the management of uncontrolled blood pressure (BP) during postpartum period. This retrospective study included 209 women diagnosed in hospital with hypertensive disorders during pregnancy and had uncontrolled BP after delivery between January 2018 to December 2020 Uncontrolled BP was defined as persistent elevation of systolic BP ≥ 160 mm Hg or diastolic BP ≥ 110 mm Hg. Patients were divided into 2 groups: nicardipine (N = 53; continuous nicardipine infusion and additional bolus of labetalol or hydralazine) and control (N = 156; consecutive bolus of labetalol or hydralazine). BP data were analyzed using the Mann–Whitney U and χ 2 tests by dividing the time interval of 4 hours by the delivery time. The highest BP trends showed that the mean values of both systolic and diastolic BP immediately before delivery were higher in the nicardipine group than in the control. After 8 to 12 hours following delivery, both systolic and diastolic BP were lower in the nicardipine group than in the control. Subsequently, 16 to 20 hours after delivery, both systolic and diastolic BP were significantly lower in the nicardipine group than in the control (137/80 vs 141/84 mm Hg). Initially, the proportions of uncontrolled BP in the nicardipine group were higher than those in the control; however, it then became lower at all time intervals 8 hours after delivery. The proportions of patients who received additional antihypertensive agents and the median cumulative dosages were lower in the nicardipine group than in the control. Continuous infusion of nicardipine can help manage uncontrolled BP during the postpartum period.

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Efficacy of low-dose nicardipine for emergent treatment of severe postpartum hypertension in maternal intensive care units: An observational study

Cited by 6 publications

References 23 publications

Effect of Comprehensive Nursing Intervention Under Internet-Based WeChat Platform Education on Postoperative Recovery of Puerperae Undergoing Cesarean Section

Effect of Comprehensive Nursing Intervention Under Internet-Based WeChat Platform Education on Postoperative Recovery of Puerperae Undergoing Cesarean Section

Effects of intravenous nicardipine followed by oral labetalol in combination with nifedipine controlled-release tablet on severe peripartum hypertension

Use of continuous infusion of nicardipine to control persistent postpartum hypertension: A retrospective study

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