Efficacy of lanolin and bovine type I collagen in the treatment of childhood anal fissures: A prospective, randomized, controlled clinical trial

Büyükyavuz, Behçet İlker; Savaş, Çağrı; Duman, Levent

doi:10.1007/s00595-009-4141-3

Cited by 7 publications

(3 citation statements)

References 34 publications

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“…The acidity inherent to policresulen in contact with the bloody tissue may also be associated with anal burning and itching 8 . The placebo group received ointment containing petrolatum and lanolin, which have a barrier effect and may be associated with the feeling of anal comfort and freshness 29 . Like any work, this study has limitations.…”

Section: Discussion Discussion Discussion Discussion Discussionmentioning

confidence: 99%

Postoperative topical analgesia of hemorrhoidectomy with policresulen and cinchocaine: a prospective and controlled study

Junior

Kotze

Rocha

et al. 2014

Rev. Col. Bras. Cir.

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OBJECTIVE: To evaluate the effects of topical policresulen and cinchocaine in the postoperative pain behavior of open hemorrhoidectomy.METHODS: We conducted a prospective, double-blinded, controlled study. The control group received the usual guidelines with oral medications. The topical treatment group received, in addition, the application of the ointment and was comprised of two subgroups (policresulen + cinchocaine, and placebo). Pain intensity was recorded with the visual analogue scale.RESULTS: 43 patients were operated on: control group - n = 13, one excluded; placebo - n = 15; and policresulen + cinchocaine - n = 15. The mean age was 45.98 years and 37.2% were men. The average pain intensity was 4.09 (immediate postoperative), 3.22 (hospital discharge), 5.73 (day 1) , 5.77 (day 2), 5.74 (day 3), 5.65 (day 7), 5.11 (day 10), 2.75 (day 15) and 7.70 (first bowel movement), with no difference between groups in all periods.CONCLUSION: This study showed no reduction in pain after hemorrhoidectomy with the use of topical policresulen and cinchocaine.

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Section: Discussion Discussion Discussion Discussion Discussionmentioning

confidence: 99%

Postoperative topical analgesia of hemorrhoidectomy with policresulen and cinchocaine: a prospective and controlled study

Junior

Kotze

Rocha

et al. 2014

Rev. Col. Bras. Cir.

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“…However, HPA Lanolin ® has proven effective in preserving the integrity of the nipples and areolas in mothers who have maintained a constant film of the product while breastfeeding, showing lower rates of trauma and pain 1 . It has also been found effective in the treatment of anal fissures in children by applying lanolin cream in the perianal area twice a day 2 .…”

Section: Discussionmentioning

confidence: 99%

Efficacy of HPA Lanolin® in treatment of lip alterations related to chemotherapy

et al. 2013

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The side effects of chemotherapy on the lips may cause esthetic and functional impact and increase the risk of infection. HPA Lanolin® is an option for supportive therapy because it has anti-inflammatory, antimicrobial and moisturizing properties.Objective:To evaluate the efficacy of this product in the prevention of lip alterations in a population of patients undergoing chemotherapy. Material and Methods:Patients undergoing chemotherapy (n=57) were examined and distributed into two groups: study (used HPA Lanolin®) and control (without supportive therapy on the lips). We evaluated the patients two weeks after chemotherapy, registering oral alterations, symptoms of pain, discomfort, limitation of mouth opening and dehydration, classified according to a visual analogue scale. Results:Patients who used HPA Lanolin® had lower dehydration and experienced improvement of lip dryness (p<0.001). The main symptoms were dehydration, discomfort, limitation of mouth opening, pain. The main clinical signs were dry lips, mucositis, cheilitis, hematoma, swelling and cracking. We found no difference concerning the variables of pain, discomfort, and limitation of mouth opening between the study and control group. Conclusions:We suggest that HPA Lanolin® is effective in reducing the symptoms of dehydration and the signs of lip dryness resulting from toxicity of chemotherapy, proving to be an interesting alternative supportive therapy for cancer patients.

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“…Nearly three quarters of this cohort applied purified lanolin to their nipples in the first week of breastfeeding. Lanolin is extracted from sheep wool and is chemically a wax "ultrarefined" to remove free lanolin alcohols to a level lower than 1.5% (Abou-Dakn, Fluhr, Gensch, several therapeutic purposes including healing anal fissures in children and preventing lip breakdown in adults undergoing chemotherapy (Büyükyavuz, Savas, & Duman, 2010;Santos et al, 2013). Chvapil, Gaines, and Gilman (1988), in their detailed study of lanolin and wound healing in piglets, suggested that lanolin may Süntar et al (2011), for example, found that a preparation of sage and oregano oils "displays remarkable wound healing activity" and is both bactericidal and fungicidal.…”

Section: Wound Healing and Lanolin Usementioning

confidence: 99%

Topical Treatments Used by Breastfeeding Women to Treat Sore and Damaged Nipples

Buck¹,

Amir²,

Donath³

2015

Clin Lactation

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Background: Nipple pain and trauma are frequent complaints of new mothers, and a variety of treatments have been proposed and investigated for efficacy. Numerous studies have examined the efficacy of nipple creams, but there is no published data describing patterns of use in breastfeeding women.Aim: To describe the use of topical nipple treatments by a cohort of first-time mothers in AustraliaMethods: A cohort of 360 nulliparous women were recruited in Melbourne, Australia, and the question, “In the last week, have you used any creams or ointments on your nipples?” was included in a questionnaire on breastfeeding practices administered at 6 time points.Results: In the first week after giving birth, 91% (307/336) of women used a topical treatment on their nipples. The most popular treatment was purified lanolin, with nearly three quarters of women (250/336) reporting its use. At 8 weeks postpartum, 37% (129/345) continued to use topical treatments, and 94% (320/340) of women continued to breastfeed.Conclusion: Widespread use of topical nipple creams is concerning not only because it may indicate a high rate of nipple pain but also because this is a disruption to the natural environment where the newborn is establishing breastfeeding.

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Efficacy of lanolin and bovine type I collagen in the treatment of childhood anal fissures: A prospective, randomized, controlled clinical trial

Abstract: Our data suggest that topical lanolin ointment and bovine type I collagen spray are effective in the treatment of acute anal fissure in children.

Cited by 7 publications

References 34 publications

Postoperative topical analgesia of hemorrhoidectomy with policresulen and cinchocaine: a prospective and controlled study

Postoperative topical analgesia of hemorrhoidectomy with policresulen and cinchocaine: a prospective and controlled study

Efficacy of HPA Lanolin® in treatment of lip alterations related to chemotherapy

Topical Treatments Used by Breastfeeding Women to Treat Sore and Damaged Nipples

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