Efficacy of Jianpi Liqi therapy for functional dyspepsia

Ye, Jintong; Dai, Yunkai; Li, Dan-Yan; Zhang, Yunzhan; Huang, Mei‐Chuan; Chen, Weijing; Li, Ru-Liu; Hu, Ling

doi:10.1097/md.0000000000016607

Cited by 4 publications

(2 citation statements)

References 55 publications

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“…The majority of the herbal formulas in these RCTs have effects that fortify the spleen and promote digestion ( Li et al, 2014 ; Cui et al, 2015 ), tonify Qi and fortify the spleen ( Hu et al, 2007 ; Qiu and Zhang, 2013 ; Wang et al, 2018 ), or tonify Qi and Blood or Yin ( Kuang et al, 2009 ; Cheon et al, 2017 ). An earlier systematic review reported that invigorating the spleen and regulating Qi therapy is more effective in alleviating symptoms of functional dyspepsia than conventional treatment ( Ye et al, 2019 ). Therefore, it can be assumed that THM, which strengthens the function of the spleen and stomach, encourages digestion, and relieves deficiencies, may be effective for patients with cancer who have anorexia.…”

Section: Discussionmentioning

confidence: 99%

Traditional herbal medicine for anorexia in patients with cancer: a systematic review and meta-analysis of randomized controlled trials

et al. 2023

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Background: The purpose of this systematic review and meta-analysis was to evaluate the efficacy and safety of traditional herbal medicine (THM) for improving anorexia in patients with cancer.Methods: We searched for randomized controlled trials (RCTs) that evaluated orally administered THM for cancer-related anorexia using 10 databases from the inception to 1 August 2021. The primary outcome was an improvement in anorexia, measured with the total effective rate (TER) or visual analog scale (VAS). The secondary outcomes were the changes in body weight, the Karnofsky performance scale, acylated ghrelin, and adverse events. We used the Cochrane risk of bias assessment tool and the Grading of Recommendations Assessment, Development, and Evaluation method to assess the quality of the studies and the quality of the evidence.Results: A total of 26 RCTs were included, of which 23 were subjected to quantitative analysis. THM showed a significant improvement in anorexia measured with the TER [risk ratio (RR) 1.12, 95% confidence intervals (CI) 1.04–1.20] than appetite stimulants with moderate quality evidence and in the Karnofsky performance scale (RR 1.38, 95% CI 1.12–1.70) with low quality evidence but not in body weight gain (RR 0.98, 95% CI 0.80–1.20). THM showed a significant improvement in anorexia measured with the TER (RR 1.74, 95% CI 1.23–2.48) compared with usual care with low-quality evidence but did not significantly improve the VAS score (mean difference 0.72, 95% CI 0.00–1.43) or the level of acylated ghrelin (mean difference 0.94, 95% CI 1.08–2.97). There were no serious adverse events.Conclusion: This review suggests that THM may be considered a safe alternative therapeutic option for improving anorexia in patients with cancer. Nonetheless, more rigorous RCTs are needed due to methodological limitations.Systematic Review Registration:https://www.crd.york.ac.uk/prospero, identifier CRD42021276508.

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Section: Discussionmentioning

confidence: 99%

Traditional herbal medicine for anorexia in patients with cancer: a systematic review and meta-analysis of randomized controlled trials

et al. 2023

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“…A delay in gastric emptying is associated with decreased anterior gastric motility, while the underlying cause of anterior gastric inactivity has not been identified (13). Other causes of dyspepsia include fundus movement disorders, visceral hypersensitivity, genetics, Helicobacter pylori infection, and psychosocial problems (14,15). Psychological factors are also associated with dyspepsia.…”

Section: Introductionmentioning

confidence: 99%

Quality of Life and Personality Traits in Dyspepsia Patients and Healthy Individuals: A Case-Control Study

Jamshidbeigi,

Adibi,

Mohammadi

et al. 2023

Zahedan J Res Med Sci

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Background: Dyspepsia is a common disorder that puts much socio-economic pressure on patients due to its high prevalence. Various factors can cause this disorder. Objectives: This study investigated the relationship between dyspepsia, quality of life, and personality traits. Methods: This case-control study selected 50 people with dyspepsia and 50 healthy people by simple random method. Patients' demographic information was recorded using a researcher-made checklist. Then, the WHOQOL-BREF questionnaire measured the quality of life, and the NEO-FFI-60 questionnaire assessed personality traits. Finally, the data were analyzed using a chi-square test, independent t-test, and multivariate linear and logistic regression by SPSS software version 22 at the significance level of 0.05. Results: The mean score of anger was higher in people with dyspepsia than in healthy people (P = 0.000), but other indicators were higher in healthy people than in people with dyspepsia (P < 0.05). Finally, the personality traits of anger, acceptance of new experiences, and conscientiousness had a significant relationship with quality of life in people with dyspepsia (P < 0.05). Conclusions: Dyspepsia reduces the quality of life and affects the personality traits of individuals. Thus, improving dyspepsia can improve patients' personality traits and quality of life.

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Agreement of gastroenterologists in traditional Chinese medical differential diagnosis of functional dyspepsia compared with traditional Chinese medical practitioners: A prospective, multicenter study

Song

Yang

et al. 2020

J of Digest Diseases

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ObjectiveTo compare the performance of gastroenterologists major in western medicine in diagnosing traditional Chinese medicine (TCM) syndrome types of functional dyspepsia (FD), postprandial distress (PDS) and epigastric pain syndromes (EPS) based on the main symptoms, with that of traditional TCM practitioners in outpatient services.MethodsPatients with PDS or EPS were enrolled in the study from six tertiary referral centers between January 2016 and December 2017. Their symptoms were first diagnosed by medical doctors, and then by the TCM practitioners. The diagnostic agreement between the gastroenterologists and the TCM practitioners was calculated. The patients’ data and their types of FD syndrome were collected and analyzed.ResultsIn total 160 patients, including 81 with PDS and 79 with EPS were enrolled. The total diagnostic consistency rate between the gastroenterologists and TCM practitioners was 86.3%, while that of PDS and EPS was 85.2% and 87.3%, respectively. The most common type of PDS diagnosed by TCM practitioners was liver‐stomach disharmony syndrome (33.3%), spleen deficiency and qi‐stagnation syndrome (33.3%), while that for EPS was liver‐stomach disharmony syndrome (36.7%).ConclusionsGastroenterologists had a high diagnostic agreement about the types of FD syndromes based on differential diagnosis of the main symptoms, compared with TCM practitioners. This may aid gastroenterologists in selecting Chinese medicine for FD‐based on syndrome differentiation.

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Efficacy of Jianpi Liqi therapy for functional dyspepsia

Cited by 4 publications

References 55 publications

Traditional herbal medicine for anorexia in patients with cancer: a systematic review and meta-analysis of randomized controlled trials

Traditional herbal medicine for anorexia in patients with cancer: a systematic review and meta-analysis of randomized controlled trials

Quality of Life and Personality Traits in Dyspepsia Patients and Healthy Individuals: A Case-Control Study

Agreement of gastroenterologists in traditional Chinese medical differential diagnosis of functional dyspepsia compared with traditional Chinese medical practitioners: A prospective, multicenter study

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