Efficacy of Ivermectin (Pour on Formulation) Against Ectoparasites in Sheep

Abstract

The research has been carried out from February to March 2005 on 20 sheep (infested and non infested with ectoparasites) of both sexes aged upto 3 to 4 years at the animal house of Veterinary Clinic, Bangladesh Agricultural University, Mymensingh to study the efficacy of ivermectin pour on (Ivermec® Pour on, Ethical Drugs Ltd., Dhaka, Bangladesh) against ectoparasites and its effect on certain haematological (Hb, TEC and PCV) parameters and body weight gain. Fifteen sheep heavily infested with different ectoparasites were randomly divided into 3 equal groups (groups B, C and D) consisting of 5 sheep in each. Another 5 sheep free from any ectoparasitic infestation were kept as uninfested control group (group A). Topical ivermectin preparation was administered at the dose rate of 400 ?g/kg body weight (pour on) and 500 ?g/kg body weight (pour on) in groups C and D respectively whereas sheep of group B was kept as infested control. The therapeutic efficacy of ivermectin was 100% against ectoparasites (lice and tick) after 7 days of treatment. The mean body weight of the sheep of treated groups (C and D) were increased after treatment with ivermectin, on day 28 post treatment. Similarly, total erythrocyte count (TEC) and hemoglobin (Hb) content was increased significantly. However, PCV was also influenced appreciably. From this experiment, it may be suggested that ivermectin is a very much suitable broad spectrum anthelmintic for sheep and its pour on formulation may be used effectively and conveniently to treat ectoparasitic infestations.

Anthelmintic efficacy of some medicinal plants to control mange in goat in Bangladesh

“…The hair coat of the infected control group A became more and discolored. This result was in agreement with the findings of Razu et al (2010) and Hanif et al (2005). The efficacy of three herbal and one patent drug against mange infestation in goat.…”

Epidemiology of Sheep Lice and Efficacy Evaluation of 60% Diazinon and 1% Ivermectin against Bovicola ovis in Sayint District, South Wollo, Ethiopia

“…The overall in-vivo e cacy of 1% Ivermectin was 81%, which is below the standard for in-vivo trials set limit (98-100%), suggestive of drug resistance. This result is far lower than the ndings of [49], who reported that Ivermectin was 100% effective against sheep lice based on pour on formulations [19,47,50]. The probable reason why reduced e cacy of 1% Ivermectin injection against Bovicola ovis could be associated with prolonged and inappropriate use of the drug, the frequent application of 1% Ivermectin drug with the same brand without rotation with other insecticide classes.…”

Innovative anthelmintic based on mechanochemical technology and their efficacy against parasitic infection of sheeps

“…Innovative antiparasitic drugs have been developed and proposed for veterinary practice, having a broad spectrum of action against several animal parasites. These drugs were based on anthelmintics from the class of macrocyclic lactones with high activity against nematodes and ectoparasites of animals [ 4 ]. Another promising anthelmintics class is benzimidazoles, which are active against a wide range of helminths [ 5 , 6 ].…”