Efficacy of Intravitreal Bevacizumab With Panretinal Photocoagulation Followed by Ahmed Valve Implantation in Neovascular Glaucoma

Abstract

Intravitreal bevacizumab (Avastin) with PRP followed by Ahmed valve implantation appears to be effective in the management of NVG.

Aqueous shunts for glaucoma

“…Most trials enrolled adults only, though Pakravan 2007 examined children with pediatric aphakic glaucoma. Three studies included only participants with neovascular glaucoma (Arcieri 2015; Mahdy 2013; Teixeira 2012), while the remainder of studies included a combination of glaucoma subtypes. The smallest trial enrolled 11 participants (Desai 2013), and the largest trial enrolled 276 participants (ABC 2011).…”

“…Two trials compared early aqueous suppression versus a standard medication regimen for postoperative increases in IOP (Law 2016; Pakravan 2014). Four trials evaluated an anti-vascular endothelial growth factor (VEGF) agent, with one trial using ranibizumab, Desai 2013, and three trials using bevacizumab (Arcieri 2015; Mahdy 2013; Rojo-Arnao 2011). Two trials evaluated a corticosteroid, with one trial comparing intravitreal triamcinolone versus none (Teixeira 2012), and another trial comparing topical dexamethasone versus topical ketorolac (Yuen 2011).…”

Beneficial Effects of Adjuvant Intravitreal Bevacizumab Injection on Outcomes of Ahmed Glaucoma Valve Implantation in Patients with Neovascular Glaucoma: Systematic Literature Review

“…The remaining 6 articles with full text that met the inclusion criteria were assessed and included in this systematic literature review. [14][15][16][17][18][19] A flow diagram of the search results is presented in Figure 1. In total, 256 eyes of 252 patients were included in this systematic literature review.…”

Reply: Prophylactic treatment of retinal breaks – a systematic review

“…Concerning the combined therapy (IVB injection plus AGV implantation) for NVG, several papers have been published (Mahdy et al 2013;Sevim et al 2013;Zhou et al 2013;Kang et al 2014). However, of these studies, various researchers carried out the IVB injection at different times.…”

“…However, of these studies, various researchers carried out the IVB injection at different times. In Mahdy's study (Mahdy et al 2013), they performed AGV implantation 2 weeks after a single IVB injection. In Kang's study (Kang et al 2014), AGV implantation was performed between 1 and 20 days after IVB.…”