“…In this study, therefore, a continuous infusion of 0.4 lg kg -1 hour -1 dexmedetomidine was thus administered without a loading dose from induction until the end of the Trendelenburg position. 30 No severe hemodynamic instability was noted in either group. MBP in Group D was slightly lower (3%-6%) than that in Group C from the T4 time point, which was 30 minutes after ST position.…”
“…In this study, therefore, a continuous infusion of 0.4 lg kg -1 hour -1 dexmedetomidine was thus administered without a loading dose from induction until the end of the Trendelenburg position. 30 No severe hemodynamic instability was noted in either group. MBP in Group D was slightly lower (3%-6%) than that in Group C from the T4 time point, which was 30 minutes after ST position.…”
“…Recently, patient-centered outcomes such as quality of recovery scores have been used as a valid measurement of clinical impact for other analgesic interventions. [51][52][53][54] Future studies examining TAP block should incorporate patient-centered outcomes into their designs to provide additional information regarding the clinical impact of TAP block on recovery of surgical patients.…”
TAP block is an effective strategy to improve early and late pain at rest and to reduce opioid consumption after laparoscopic surgical procedures. In contrast, the TAP block was not superior compared with control to reduce early and late pain during movement. Preoperative administration of a TAP block seems to result in greater effects on postoperative pain outcomes. We also detected a local anesthetic dose response on late pain and postoperative opioid consumption.
“…48,49 In several studies, intraoperative administration of dexmedetomidine reduced emergence agitation in children by 57% to 70% compared with control groups. 50,51 Kim et al 52 reported that intraoperative dexmedetomidine infusion significantly reduced emergence agitation after nasal surgery in adult patients. Consistent with previous results, 52 dexmedetomidine was also effective in reducing emergence agitation in our study.…”
When used in conjunction with TIVA, intraoperative dexmedetomidine blunts surgical stress responses to an extent comparable to combined epidural and general anesthesia without compromising hemodynamic stability and with minimal adverse effects during the intraoperative period.
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