Efficacy of Intra-Articular Hyaluronic Acid Injections in Delaying Total Knee Arthroplasty and Safety Evaluation in Primary Knee Osteoarthritis: Analysis Based on Health Insurance Review and Assessment Service (HIRA) Claim Database in Korea
Jun-Gu Park,
Juho Sim,
Seung-Beom Han
Abstract:Background
This retrospective cohort study aimed to evaluate the efficacy of intra-articular hyaluronic acid (IA-HA) injections in delaying total knee arthroplasty (TKA) and the safety of IA-HA according to IA-HA type and combination with intra-articular corticosteroid (IA-CS) using a large health insurance claim database.
Methods
The study population included patients aged ≥ 50 years with a first diagnosis of knee osteoarthritis (KOA) between 2009 and 2014, who underwent TKA by 2020, using the Health Insura… Show more
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