Efficacy of Interventions for Improving Antiretroviral Therapy Adherence in HIV/AIDS Cases at PIMS, Islamabad

Uzma, Qudsia; Emmanuel, Faran; Ather, Uzma; Zaman, Shakila

doi:10.1177/1545109710383175

Cited by 24 publications

(30 citation statements)

References 11 publications

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“…Strategies using cellular technology (short message service communication) have demonstrated improvement in adherence and HIV-1 RNA. Methods ranged from texting dosing reminders with or without requesting a response (66–68) to texting weekly check-ins from the clinic with telephone follow-up for those requesting it (69). One study found better ART adherence was achieved with use of texting with expected reply (interactive) than simple 1-way reminders (66).…”

Section: Guidelinesmentioning

confidence: 99%

Guidelines for Improving Entry Into and Retention in Care and Antiretroviral Adherence for Persons With HIV: Evidence-Based Recommendations From an International Association of Physicians in AIDS Care Panel

Thompson¹,

Mugavero²,

Amico³

et al. 2012

Ann Intern Med

533

460

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Description After HIV diagnosis, timely entry into HIV medical care and retention in that care are essential to the provision of effective antiretroviral therapy (ART). ART adherence is among the key determinants of successful HIV treatment outcome and is essential to minimize the emergence of drug resistance. The International Association of Physicians in AIDS Care convened a panel to develop evidence-based recommendations to optimize entry into and retention in care and ART adherence for people with HIV. Methods A systematic literature search was conducted to produce an evidence base restricted to randomized, controlled trials and observational studies with comparators that had at least 1 measured biological or behavioral end point. A total of 325 studies met the criteria. Two reviewers independently extracted and coded data from each study using a standardized data extraction form. Panel members drafted recommendations based on the body of evidence for each method or intervention and then graded the overall quality of the body of evidence and the strength for each recommendation. Recommendations Recommendations are provided for monitoring of entry into and retention in care, interventions to improve entry and retention, and monitoring of and interventions to improve ART adherence. Recommendations cover ART strategies, adherence tools, education and counseling, and health system and service delivery interventions. In addition, they cover specific issues pertaining to pregnant women, incarcerated individuals, homeless and marginally housed individuals, and children and adolescents, as well as substance use and mental health disorders. Recommendations for future research in all areas are also provided.

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Section: Guidelinesmentioning

confidence: 99%

Guidelines for Improving Entry Into and Retention in Care and Antiretroviral Adherence for Persons With HIV: Evidence-Based Recommendations From an International Association of Physicians in AIDS Care Panel

Thompson¹,

Mugavero²,

Amico³

et al. 2012

Ann Intern Med

533

460

View full text Add to dashboard Cite

show abstract

“…short message services [SMS]) have also been shown to improve adherence and viral outcomes and may be cost-effective [72-78]. Depending on resources, these can involve one-way reminder text messages or pages [73, 76], text messages requiring patient response [74, 77], or phone calls allowing for interactive conversations about adherence [75]. Interventions requiring some form of patient response may be more effective compared to one-way reminders [77].…”

Section: Strategies For Improving Retention and Adherencementioning

confidence: 99%

Retention in Care and Medication Adherence: Current Challenges to Antiretroviral Therapy Success

Holtzman

Brady

Yehia

2015

Drugs

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Health behaviors, such as retention in HIV medical care and adherence to antiretroviral therapy (ART), pose major challenges to reducing new HIV infections, addressing health disparities, and improving health outcomes. Andersen's Behavioral Model of Health Service Use provides a conceptual framework for understanding how patient and environmental factors affect health behaviors and outcomes, which can inform the design of intervention strategies. Factors affecting retention and adherence among persons with HIV include patient predisposing factors (e.g. mental illness, substance abuse), patient enabling factors (e.g. social support, reminder strategies, medication characteristics, transportation, housing, insurance), and health care environment factors (e.g. pharmacy services, clinic experiences, provider characteristics). Evidence-based recommendations for improving retention and adherence include 1) systematic monitoring of clinic attendance and ART adherence; 2) use of peer or paraprofessional navigators to re-engage patients in care and help them remain in care; 3) optimization of ART regimens and pharmaceutical supply chain management systems 4) provision of reminder devices and tools; 5) general education and counseling; 6) engagement of peer, family, and community support groups; 7) case management; and 8) targeting patients with substance abuse and mental illness. Further research is needed on effective monitoring strategies and interventions that focus on improving retention and adherence, with specific attention to the health care environment.

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“…Another cell phone [27] intervention examined the efficacy of using cell phone reminders for ART adherence in Pakistan. This controlled trial was conducted with 76 men and women randomized to receive either the intervention condition which consisted of participant involved counseling and weekly cell phone reminders over the course of a month or the control condition which received routine counseling.…”

Section: Medication Adherencementioning

confidence: 99%

“…Kalichman et al [26] and Uzma et al [27] found positive effects on adherence for both objective measures (i.e. unannounced pill count and viral load) as well as subjective measures (i.e.…”

Section: Medication Adherencementioning

confidence: 99%

Recent Advances (2011-2012) in Technology-Delivered Interventions for People Living with HIV

Pellowski

Kalichman

2012

Curr HIV/AIDS Rep

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Technology is rapidly advancing and becoming a cost effective option for intervention delivery particularly for isolated and hard to reach populations, such as people living with HIV/AIDS. A systematic review was conducted to identify recent technology based interventions for people living with HIV. The review yielded 12 studies that were grouped by the health behavior that it addressed and then the type of technology utilized. The majority of studies reviewed focused on medication adherence and used several different technologies to deliver the intervention including SMS/text messaging, cell phones and computers. This review identified several gaps in the literature particularly the lack of technology-based interventions focusing on engagement and retention to care as well as sexual risk reduction. Suggestions for future research based on these findings are provided.

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Efficacy of Interventions for Improving Antiretroviral Therapy Adherence in HIV/AIDS Cases at PIMS, Islamabad

Cited by 24 publications

References 11 publications

Guidelines for Improving Entry Into and Retention in Care and Antiretroviral Adherence for Persons With HIV: Evidence-Based Recommendations From an International Association of Physicians in AIDS Care Panel

Guidelines for Improving Entry Into and Retention in Care and Antiretroviral Adherence for Persons With HIV: Evidence-Based Recommendations From an International Association of Physicians in AIDS Care Panel

Retention in Care and Medication Adherence: Current Challenges to Antiretroviral Therapy Success

Recent Advances (2011-2012) in Technology-Delivered Interventions for People Living with HIV

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