Efficacy of Infection Control Measures During a Nosocomial Outbreak of Disseminated Aspergillosis Associated with Hospital Construction

Outbreaks of infectious diseases in stem cell transplant units: a silent cause of death for patients and transplant programmes

“…[10][11][12][13] However, the benefits conferred by HEPA filtration require appropriate maintenance, monitoring of positive pressure and education of staff and patients. [14][15][16] Previous colonisation or invasive fungal infection during periods of chemotherapy-induced neutropenia increase the risk of re-emergence of infection in the post transplant period. 4 Contamination of water supplies may also be a source of fungal infection in the transplant recipient.…”

Health hazard evaluation report: HETA-93-0846-2386, Providence Ambulatory Health Care Foundation, Inc., Central Health Care Center, Providence, Rhode Island.

“…Research has shown it to be effective at reducing air concentrations of Aspergillus spores which are of a similar size range to aerosolized M. tuberculosis particles. 16,17,18 HEPA filters can be used to clean air before it is recirculated into other parts of a facility or back into the same area, or exhausted to the outside. HEPA filtration systems require proper installation, periodic leak testing, and meticulous maintenance.…”

Health hazard evaluation report: HETA-93-0751-2408, Providence Ambulatory Health Care Foundation, Inc., Fox Point Health Care Center, Providence, Rhode Island.

“…Research has shown it to be effective at reducing air concentrations of Aspergillus spores which are of a similar size range to aerosolized M. tuberculosis particles. 17,18,19 HEPA filters can be used to clean air before it is recirculated into other parts of a facility or back into the same area, or exhausted to the outside. HEPA filtration systems require proper installation, periodic leak testing, and meticulous maintenance.…”