Efficacy of individual and group hypnotherapy in irritable bowel syndrome (IMAGINE): a multicentre randomised controlled trial

Flik, Carla E.; Laan, Wijnand; Zuithoff, Nicolaas P.A.; Rood, Yanda R. van; Smout, A. J. P. M.; Weusten, Bas L.; Whorwell, Peter J.; Wit, Niek J. de

doi:10.1016/s2468-1253(18)30310-8

Cited by 85 publications

(91 citation statements)

References 45 publications

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“…Due to the relative lack in therapist availability, clinical implementation of these therapies is still limited. Recent attempts to reduce resource use without compromising effectiveness may assist in making psychological treatment more widely available; for example, group hypnotherapy, Internet‐delivered exposure‐based CBT, and home‐based CBT . In that light, it will be interesting to explore whether these developments can affect long‐term quality of life and well‐being in patients with IBS.…”

Section: Discussionmentioning

confidence: 99%

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Reduction in IBS symptom severity is not paralleled by improvement in quality of life in patients with irritable bowel syndrome

Weerts

Vork

Mujagic

et al. 2019

Neurogastroenterology Motil

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Background Irritable bowel syndrome (IBS) is a brain‐gut disorder, of which the natural course varies between patients and is difficult to predict. This study aimed to evaluate symptom evolution over a 5‐year follow‐up period and to identify baseline predictors for symptom severity and quality of life (QoL) at follow‐up. Methods Maastricht IBS cohort participants completed questionnaires upon inclusion regarding demographics and lifestyle, gastrointestinal (GI) symptoms, anxiety and depression, and QoL. The same questionnaires, in addition to others, were completed after 5 years. Rome criteria were confirmed face‐to‐face at initial enrollment and through telephonic interviews at follow‐up. Key Results At a mean follow‐up of 4.7 years, 379 patients were approached of whom 203 (53.7%) responded. Of these, 161 were reached by telephone and analyzed; 49 (30.4%) did not fulfill the Rome III criteria at follow‐up and had lower levels of GI symptoms and GI‐specific anxiety compared to those remaining Rome III‐positive (P < 0.001). However, Rome III‐negative patients had comparable levels of QoL and life satisfaction, comorbid anxiety and depression, work absenteeism, and impaired productivity. No baseline predictors were found for being Rome III‐positive or Rome III‐negative. However, greater age and lower baseline physical QoL predicted lower physical QoL at follow‐up (P < 0.005 and P < 0.01, respectively), while lower baseline mental QoL predicted lower mental QoL at follow‐up (P = 0.005). Additionally, higher anxiety and depression scores at follow‐up were associated with lower QoL and life satisfaction at follow‐up (P < 0.001). Conclusions and Inferences Long‐term QoL and general well‐being might depend on concurrent psychological symptoms, rather than GI symptom improvement.

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Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Reduction in IBS symptom severity is not paralleled by improvement in quality of life in patients with irritable bowel syndrome

Weerts

Vork

Mujagic

et al. 2019

Neurogastroenterology Motil

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“…In a randomized controlled trial of the group approach compared to standard medical treatment, group hypnotherapy has been shown to be effective (61% vs. 41%), with durable effects being maintained over a year posttreatment. Moreover, while preliminary data from two recently completed randomized head to head trials have shown marginally better response rates in individualized vs. group hypnotherapy, both trials found that group therapy was not significantly inferior to individualized therapy, suggesting that group hypnotherapy may be a way of improving access. One of the drawbacks of group hypnotherapy is that the package has to be generic, whereas for the more severe, refractory cases seen in tertiary care, who have more complex needs, treatment needs to be individualized.…”

Section: Areas For Future Research and Developmentmentioning

confidence: 97%

Gut‐focused hypnotherapy for Functional Gastrointestinal Disorders: Evidence‐base, practical aspects, and the Manchester Protocol

Vasant

Whorwell

2019

Neurogastroenterology Motil

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Background Despite their high prevalence and advances in the field of neurogastroenterology, there remain few effective treatment options for functional gastrointestinal disorders (FGIDs). It is recognized that approximately 25% of sufferers will have symptoms refractory to existing therapies, causing significant adverse effects on quality of life and increased healthcare utilization and morbidity. Gut‐focused hypnotherapy, when delivered by trained therapists, has been shown to be highly effective in severe refractory FGIDs. However, hypnotherapy continues to be surrounded by much misunderstanding and skepticism. Purpose The purpose of this review is to provide a contemporary overview of the principles of gut‐focused hypnotherapy, its effects on gut‐brain interactions, and the evidence‐base for its efficacy in severe FGIDs. As supplementary material, we have included a hypnotherapy protocol, providing the reader with an insight into the practical aspects of delivery, and as a guide, an example of a script of a gut‐focused hypnotherapy session.

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“…Ferner betrachtete diese Metaanalyse nur den Effekt beim therapierefraktären RDS, weshalb der Effekt bei milderen Ausprägungen zu untersuchen bleibt [97]. Diesbezüglich berichtet eine aktuelle multizentrische, randomisiert-kontrollierte Studie von dem Einfluss einer individuell oder gruppenbezogen vermittelten Hypnotherapie bei RDS-Patienten, deren Konsultation im Primär-und Sekundärzentrum stattfand [98]. Im Vergleich zu einer pädagogischen Thera-piegruppe resultierte die Hypnotherapie nach 3 Monaten in beiden Interventionsgruppen in einer signifikant höheren subjektiven Entlastung, die unter anderem mittels der Lebensqualität, RDS-Symptome und psychischer Beschwerden ermittelt wurde; diese positiven Effekte der Hypnotherapie hielten auch über einen Verlauf von 12 Monaten an [98], sodass die Studie einen Hinweis auf die andauernde Wirksamkeit der Hypnotherapie auch bei milderen RDS-Verläufen liefert.…”

Section: Hypnotherapieunclassified

Die Rolle Der Psychotherapie Beim Reizdarmsyndrom

Weibert

Stengel

2019

Psychother Psych Med

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ZusammenfassungDas Reizdarmsyndrom ist eine häufige funktionelle gastrointestinale Störung, die aufgrund wiederkehrender gastrointestinaler Beschwerden wie Bauchschmerzen oder Stuhlveränderungen die Lebensqualität erheblich beeinträchtigen kann. Basierend auf dem biopsychosozialen Krankheitsmodell wird die Ausprägung des Reizdarmsyndroms durch die Kombination von veränderten physiologischen Prozessen, sozialen Aspekten und psychischen Faktoren beeinflusst. Während der Fokus bisher auf der Linderung der Darmbeschwerden mittels Diät sowie medikamentöser Therapie lag, stellen Psychotherapieverfahren angesichts der starken Assoziation mit psychischen Komorbiditäten (u. a. Depression, Angststörung) zunehmend alternative oder ergänzende Behandlungsmethoden mit mittlerweile sehr guter Evidenz dar. Grundsätzlich können zusätzliche psychische Begleitsymptome die Wahrscheinlichkeit komplizierter Krankheitsverläufe erhöhen, wobei sich psychische Symptome und Darmbeschwerden maßgeblich gegenseitig beeinflussen. Mithilfe von kognitiver Verhaltenstherapie, psychodynamischer Psychotherapie, Hypnotherapie, achtsamkeitsbasierter Therapie und anderen psychotherapeutischen Verfahren sollen die Krankheitsbewältigung und -kontrolle gesteigert und fehlregulierte kognitive Prozesse umstrukturiert werden. In dieser Übersichtsarbeit fokussieren wir uns auf den psychosozialen Aspekt des Reizdarmsyndroms und diskutieren den Nutzen der psychotherapeutischen Verfahren.

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Efficacy of individual and group hypnotherapy in irritable bowel syndrome (IMAGINE): a multicentre randomised controlled trial

Cited by 85 publications

References 45 publications

Reduction in IBS symptom severity is not paralleled by improvement in quality of life in patients with irritable bowel syndrome

Reduction in IBS symptom severity is not paralleled by improvement in quality of life in patients with irritable bowel syndrome

Gut‐focused hypnotherapy for Functional Gastrointestinal Disorders: Evidence‐base, practical aspects, and the Manchester Protocol

Die Rolle Der Psychotherapie Beim Reizdarmsyndrom

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