Efficacy ofTripterygium hypoglaucumHutch in Adults with Chronic Urticaria

Abstract

This study shows that the therapeutic effect of THH with cetirizine is predominant over that of cetirizine alone in adult CU. THH with cetirizine may play an important role in the therapy of CU and be a useful treatment for CU.

Efficacy and safety of Tripterygium wilfordii hook F for chronic urticaria: a systematic review and meta-analysis

“…One trial [23] applied guidance for the diagnosis and treatment of urticaria (2007). Four trials [9, 13, 17, 24] mentioned diagnostic criteria, while the remaining four trials [15, 18, 26, 28] met diagnostic criteria for urticaria.…”

“…The basic characteristics of involved studies are presented in Table 1. In treatment groups, 11 trials [15, 17, 19, 23, 25–28, 30–32] used GTT, six trials [9, 13, 16, 21, 22, 29] used TG, three trials [18, 20, 22] used THH, and one trial [14] used TwHF. The control groups used different types of second-generation antihistamines.…”

“…The control groups used different types of second-generation antihistamines. Three of these trials [9, 13, 22] used a combination with mizolastine, five trials [9, 14, 18, 19, 24] with cetirizine, nine trials [15–17, 25, 27, 28, 30–32] used desloratadine, while one trial [9] utilized loratadine. Two trials [23, 29] used ebastine, one trial [20] used terfenadine, and two trials [21, 26] used fexofenadine.…”

“…One trial [18] measured LFS and Total Efficacy Rate (TER) and another [26] only evaluated UAS. The results of four trials [20, 27, 29, 31] were described by symptom assessments.…”

“…Ten of the included trials [16–19, 22, 24–26, 28, 32] reported random sequence generation, five of which [16, 17, 19, 22, 24] were based on treatment order and the remaining five [18, 25, 26, 28, 32] were based on tables of random numbers. Only one article [18] mentioned allocation concealment, blinding method, whereas the others did not.…”