Chronic pain is one of the health problems of common concern around the world. With the increasing expectation of patients for the therapeutic effect, traditional drug therapy has been difficult to meet the needs of patients. As a new minimally invasive pain treatment technology, pulsed radiofrequency has significant clinical effect, simple operation and repeatability, and plays an important role in the treatment of chronic pain. This article reviews the application of pulsed radiofrequency in the treatment of various chronic pain, in order to provide reference for clinical treatment.