Efficacy of High Frequency Ultrasound in Localization and Characterization of Orbital Lesions

Nagaraju, Rashmi M; G, Gurushankar; Bhimarao,; Bindushree, Kadakola

doi:10.7860/jcdr/2015/13021.6428

Cited by 8 publications

(16 citation statements)

References 12 publications

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“…Among non‐ED providers, ultrasound was 91.1% (95% CI = 67.5% to 98.0%) sensitive and 98.6% (95% CI = 81.7% to 99.9%) specific (Data Supplement S1, Figure ). Note that the overall pooled sensitivity is higher than the pooled sensitivities of either subgroup due to the inclusion of Nagaraju et al . (with 100% sensitivity and 100% specificity) among the 11 studies, but exclusion of that same study from either subgroup due to uncertainty about whether ED providers performed the retinal ultrasound.…”

Section: Resultsmentioning

confidence: 99%

“…Studies were published between 1995 and 2018 with population sizes ranging from 32 to 139. Three studies were conducted in the United States, two were performed in Canada, one took place in China, one was conducted in India, one was performed in Ireland, one was conducted in Korea, one took place in Nigeria, and one was performed in Thailand . Five studies were conducted in the ED setting, two were performed in radiology departments, one was performed in an ophthalmology clinic, and three did not describe the study setting .…”

Section: Resultsmentioning

confidence: 99%

“…Three studies were conducted in the United States, two were performed in Canada, one took place in China, one was conducted in India, one was performed in Ireland, one was conducted in Korea, one took place in Nigeria, and one was performed in Thailand . Five studies were conducted in the ED setting, two were performed in radiology departments, one was performed in an ophthalmology clinic, and three did not describe the study setting . Emergency medicine providers performed the examination in six studies, radiologists performed the examination in four studies, and one study did not describe the provider specialty .…”

Section: Resultsmentioning

confidence: 99%

“…Five studies were conducted in the ED setting, two were performed in radiology departments, one was performed in an ophthalmology clinic, and three did not describe the study setting . Emergency medicine providers performed the examination in six studies, radiologists performed the examination in four studies, and one study did not describe the provider specialty . All studies used a linear probe except for Ukponmwan and Marchien, who used a curvilinear probe .…”

Section: Resultsmentioning

confidence: 99%

“…However, prior studies were limited by small sample sizes, resulting in wide ranges of potential accuracy . Since then, a number of additional studies have been published, significantly increasing the available data …”

mentioning

confidence: 99%

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Point‐of‐Care Ocular Ultrasound for the Diagnosis of Retinal Detachment: A Systematic Review and Meta‐Analysis

Gottlieb

Holladay

Peksa

2019

Academic Emergency Medicine

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Background: Ocular complaints are common presentations to the emergency department (ED). Among these, retinal detachment can cause significant vision loss if not rapidly diagnosed and referred for appropriate treatment. Point-of-care ultrasound has been suggested to identify the diagnosis rapidly when the ocular examination is limited or the ophthalmology service is not readily available. However, prior studies were limited by small sample sizes, resulting in wide ranges of potential accuracy. The primary outcome for this review was to determine the test characteristics of point-of-care ocular ultrasound for the diagnosis of retinal detachment.Methods: PubMed, CINAHL, Scopus, LILACS, the Cochrane Database of Systematic Reviews, the Cochrane Central Register of Controlled Trials, and bibliographies of selected articles were assessed for all prospective and randomized controlled trials assessing the accuracy of point-of-care ultrasound for identifying retinal detachment. Data were dual extracted into a predefined worksheet and quality analysis was performed using the QUADAS-2 tool. Data were summarized and a meta-analysis was performed with planned subgroup analyses by location and provider specialty. This review was registered with PROSPERO CRD42018097288. There was no funding for this review.Results: Eleven studies (n = 844 patients) were identified. Overall, ultrasound was 94.2% (95% confidence interval [CI] = 78.4% to 98.6%) sensitive and 96.3% (95% CI = 89.2% to 98.8%) specific for the diagnosis of retinal detachment with a positive likelihood ratio of 25.2 (95% CI = 8.1 to 78.0) and a negative likelihood ratio of 0.06 (95% CI = 0.01 to 0.25). Subgroup analysis found that ultrasound was more accurate among ED patients, but was not significantly different when performed by ED or non-ED providers.Conclusions: Point-of-care ocular ultrasound is sensitive and specific for the diagnosis of retinal detachment.Future studies should determine the ideal training protocol and the influence of color Doppler and contrastenhanced ultrasound on diagnostic accuracy. O cular complaints are common emergency department (ED) presentations, accounting for approximately 3.4% of all ED visits over a 5-year period. 1 The differential diagnosis of flashes and floaters includes posterior vitreous detachment, retinal detachment, posterior uveitis, vitreous hemorrhage, oculodigital stimulation, rapid eye movements, neovascular age-related macular degeneration, migraine with aura, occipital lobe disorders, and postural hypotension. 2 While most patients will have a benign etiology, up to 10% to 26% of patients presenting with acute onset of flashes or floaters will be diagnosed with a

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

mentioning

confidence: 99%

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Point‐of‐Care Ocular Ultrasound for the Diagnosis of Retinal Detachment: A Systematic Review and Meta‐Analysis

Gottlieb

Holladay

Peksa

2019

Academic Emergency Medicine

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Multi-parametric magnetic resonance imaging characterization of orbital lesions: a triple blind study

Russo

Strianese

Perrotta

et al. 2020

Seminars in Ophthalmology

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Ultrasound in ocular oncology: Technical advances, clinical applications, and limitations

Kadakia,

Zhang,

Yao

et al. 2023

Exp Biol Med (Maywood)

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Due to its accessibility and ability for real-time image acquisition of ocular structures, ultrasound has high utility in the visualization of the eye, especially in ocular oncology. In this minireview, we summarize the technical rationale and applications of ultrasound modalities, A-scan, B-scan, high-frequency ultrasound biomicroscopy (UBM), and Doppler measurement. A-scan ultrasound uses a transducer of 7–11 MHz, making it useful for determining the echogenicity of ocular tumors (7–8 MHz) and measuring the axial length of the eye (10–11 MHz). B-scan ultrasound operates at 10–20 MHz, which can be used for measuring posterior ocular tumors while UBM operates at 40–100 MHz to evaluate anterior ocular structures. Doppler ultrasonography allows for the detection of tumor vascularization. While ultrasonography has numerous clinical applications due to its favorable penetration compared with optical coherence tomography, it is still limited by its relatively lower resolution. Ultrasound also requires an experienced sonographer due to the need for accurate probe localization to areas of interest.

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Efficacy of High Frequency Ultrasound in Localization and Characterization of Orbital Lesions

Cited by 8 publications

References 12 publications

Point‐of‐Care Ocular Ultrasound for the Diagnosis of Retinal Detachment: A Systematic Review and Meta‐Analysis

Point‐of‐Care Ocular Ultrasound for the Diagnosis of Retinal Detachment: A Systematic Review and Meta‐Analysis

Multi-parametric magnetic resonance imaging characterization of orbital lesions: a triple blind study

Ultrasound in ocular oncology: Technical advances, clinical applications, and limitations

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