Efficacy of fluralaner in 17 dogs with sarcoptic mange

Núñez, Camilo Romero; Heredia, Rafael; Pineda, Jocelyn; Serrano, Jonathan A.; Mendoza, G. D.; Trápala, Porfirio; Cordero, Alberto M.

doi:10.1111/vde.12363

Cited by 30 publications

(19 citation statements)

References 15 publications

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“…The efficacy of the treatment was assessed weekly by clinical lesion scores and superficial skin scrapings by the same veterinarian (on days 0, 7, 14 and 21). Clinical lesion scores were evaluated as described previously, with some modifications for raccoon dogs . Briefly, 12 body sites typically involved in S .…”

Section: Case Reportsupporting

confidence: 83%

“…However, at Day 7 after fluralaner treatment, mites were not observed in all raccoon dogs (Table ). Although the response to fluralaner in this study was faster than that reported previously in dogs, further studies need to be performed to verify complete eradication and to optimize the appropriate dose and regimen required for the treatment of scabies in raccoon dogs.…”

Section: Discussionmentioning

confidence: 90%

“…It is approved as a preventive drug for flea and tick infestations in dogs and is formulated as a chewable tablet. Several studies have demonstrated the clinical efficacy of fluralaner in dogs for demodicosis and scabies …”

Section: Introductionmentioning

confidence: 99%

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Clinical efficacy of orally administered fluralaner for treatment of scabies in six free‐ranging raccoon dogs (Nyctereutes procyonoides)

Hyun

Jang²,

Hwang

et al. 2019

Veterinary Dermatology

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Background Sarcoptic mange in free‐ranging raccoon dogs (Nyctereutes procyonoides) caused by Sarcoptes scabiei is a widespread zoonotic disease that causes severe skin lesions with significant morbidity and mortality. Fluralaner is a member of the isoxazoline chemical class and is an acaricide and insecticide widely used in flea, tick and mite infections of dogs (Canis lupus familiaris). Objective To evaluate the clinical efficacy of orally administered fluralaner in free‐ranging raccoon dogs naturally infected with sarcoptic mange. Animals Six raccoon dogs rescued at the Seoul Wildlife Center between November 2017 and April 2018. Methods and materials Raccoon dogs were treated with a single dose of a chewable fluralaner tablet. Clinical lesion scoring and superficial skin scraping were performed weekly for three weeks to assess treatment efficacy; the general health was assessed daily to monitor response and observe any adverse drug reactions. Results Within seven days of treatment, a marked reduction in skin lesions was observed and mites were no longer present in skin scrapings. There was no evidence of re‐infestation and no additional drug administration was required. Conclusions and clinical importance Although this was a nonrandomized, uncontrolled study of a small number of animals, it demonstrated that fluralaner may be suitable for treating sarcoptic mange in raccoon dogs.

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Section: Case Reportsupporting

confidence: 83%

Section: Discussionmentioning

confidence: 90%

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Clinical efficacy of orally administered fluralaner for treatment of scabies in six free‐ranging raccoon dogs (Nyctereutes procyonoides)

Hyun

Jang²,

Hwang

et al. 2019

Veterinary Dermatology

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“…This compound was successfully used in parasitic skin diseases as miticidal therapy for sarcoptic mange (Romero et al, 2016) and demodicosis (Fourie et al, 2015;Duangkaew et al, 2018). Against generalized demodicosis, its administration resulted in 99.8% reduction of the mean mite observed by skin scrapings 28 days after treatment, while a 100% reduction was observed in 56 days after treatment (Fourie et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

Efficacy of fluralaner against canine generalized demodicosis

et al. 2019

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“…It is approved for use in dogs and cats for flea and tick prevention in the USA, and efficacy has been reported in the treatment of Demodex spp . and Sarcoptes scabiei in dogs. Fluralaner has been given to eight‐week‐old puppies at five times the recommended dose (280 mg/kg) with no adverse effects .…”

Section: Introductionmentioning

confidence: 99%

Fluralaner as a single dose oral treatment for Caparinia tripilis in a pygmy African hedgehog

Núñez

Waisburd²,

Pineda

et al. 2017

Veterinary Dermatology

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Efficacy of fluralaner in 17 dogs with sarcoptic mange

Abstract: Fluralaner was effective in eliminating scabies mites within 14 days and significantly resolved the clinical signs associated with sarcoptic mange within 21 days after a single dose.

Cited by 30 publications

References 15 publications

Clinical efficacy of orally administered fluralaner for treatment of scabies in six free‐ranging raccoon dogs (Nyctereutes procyonoides)

Clinical efficacy of orally administered fluralaner for treatment of scabies in six free‐ranging raccoon dogs (Nyctereutes procyonoides)

Efficacy of fluralaner against canine generalized demodicosis

Fluralaner as a single dose oral treatment for Caparinia tripilis in a pygmy African hedgehog

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