Efficacy of fluoride varnish for preventing white spot lesions and gingivitis during orthodontic treatment with fixed appliances—a prospective randomized controlled trial

Kirschneck, Christian; Christl, Jan-Joachim; Reicheneder, Claudia; Proff, Peter

doi:10.1007/s00784-016-1730-6

Cited by 53 publications

(53 citation statements)

References 23 publications

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“…The data for the secondary outcomes (PI and GI) further confirmed the findings of preceding studies, reporting a significant increase in gingival inflammation and bacterial plaque mass after the onset of orthodontic therapy with fixed appliances . Differences between the groups regarding PI and GI were not significant for any of the evaluated time points, which was also in good agreement with the results of a previous trial comparing the plaque‐ and gingivitis‐reducing properties of a fluoride‐free HAP test dentifrice and a fluoridated amine fluoride (AmF)/SnF 2 control in a study cohort of patients suffering from mild to moderate periodontitis …”

Section: Discussionsupporting

confidence: 88%

“…Following the recommendations made by the International Consensus Workshop on Caries Clinical Trials in 2004, only high caries risk orthodontic patients were recruited. Despite regularly brushing with the assigned dentifrices, both experimental groups showed a considerable increase in enamel caries during the 168‐day observation period comparable in its magnitude to findings of other clinical trials . In all comparisons made, and in particular regarding the development of more severe caries lesions ICDAS ≥code 2, the percentage of HAP group individuals affected by the new occurrence of an enamel caries lesion was consistently lower than the percentage of fluoride control group members (Table ).…”

Section: Discussionsupporting

confidence: 63%

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Impact of a non‐fluoridated microcrystalline hydroxyapatite dentifrice on enamel caries progression in highly caries‐susceptible orthodontic patients: A randomized, controlled 6‐month trial

Schlagenhauf

Kunzelmann

Hannig

et al. 2019

J of Invest & Clin Dent

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101

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Aim The aim of the present randomized, controlled trial was to compare the impact of the regular use of a fluoride‐free microcrystalline hydroxyapatite (HAP) dentifrice and a 1400 ppm fluoride control dentifrice on caries progression in 150 highly caries‐active orthodontic patients. Methods The primary outcome was the occurrence of lesions with International Caries Detection and Assessment System (ICDAS) ≥code 1 on the vestibular surfaces of teeth 15‐25 within 168 days after fixation of orthodontic brackets. Secondary outcomes were lesion development ICDAS ≥code 2, the plaque index, and the gingival index. Results In total, 147 patients were included in the intent‐to‐treat (ITT) analysis; 133 finished the study per protocol (PP). An increase in enamel caries ICDAS ≥code 1 was observed in 56.8% (ITT) and 54.7% (PP) of the HAP group participants compared with 60.9% (ITT) and 61.6% (PP) of the fluoride control group. Non‐inferiority testing (ITT and PP) demonstrated the absence of a significant difference between the groups. No significant differences in secondary outcomes were observed between the groups. Conclusion In highly caries‐active patients, the impact of the regular use of a microcrystalline HAP dentifrice on caries progression is not significantly different from the use of a 1400 ppm fluoride toothpaste (ClinicalTrials.gov: NCT02705456).

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Section: Discussionsupporting

confidence: 88%

Section: Discussionsupporting

confidence: 63%

Impact of a non‐fluoridated microcrystalline hydroxyapatite dentifrice on enamel caries progression in highly caries‐susceptible orthodontic patients: A randomized, controlled 6‐month trial

Schlagenhauf

Kunzelmann

Hannig

et al. 2019

J of Invest & Clin Dent

Self Cite

101

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“…Rough enamel surfaces cause increased plaque formation [5][6][7][8][9][10][11]. Smooth surfaces reduce bacterial adhesion [12,13].…”

Section: Discussionmentioning

confidence: 99%

“…Increased surface roughness of enamel after performing IPR could promote plaque accumulation and enamel demineralization by acids produced by cariogenic bacteria in the forming biofilm [7,8]. The application of fluoride varnishes after IPR has been recommended to alleviate this problem [9], but has been shown to be sometimes ineffective, in particular, if application frequency is too low [10]. Thus the aim of our study was to assess and compare the enamel surface quality after IPR was performed with four different commercially available systems and to study the relationship between acid penetration depth and enamel surface quality as well as the importance of remineralization.…”

Section: Introductionmentioning

confidence: 99%

Depth of acid penetration and enamel surface roughness associated with different methods of interproximal enamel reduction

et al. 2020

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Objectives To assess and compare the enamel surface quality after interproximal enamel reduction (IPR) was performed with different systems and to study the relation between acid penetration depth and enamel surface quality as well as the importance of remineralization. Methods Sixty-five extracted teeth were randomly allocated to five experimental groups: untreated control, manual with New Metal Strips, mechanical with oscillating segment (OS) discs, Safe-Tipped Bur Kit, and the Ortho-Strip, followed by 30 s of polishing with the Softflex system and the Compo-system after treating the tooth with OS discs. Mesial surfaces were demineralized for 24 h and distal surfaces were subjected to interchanging demineralization and remineralization cycles of 24 h each for 18 days. The analysis was carried out by profilometry, scanning electron microscopy, and polarization microscopy. Results After IPR and polishing, enamel roughness was reduced for all systems tested except for the Essix Safe-Tipped Bur Kit. Subsequent demineralization increased enamel roughness in all groups except controls beyond the original level prior to IPR except for IPR with New Metal Strips or Ortho-Strips and subsequent polishing. Cyclic demineralization and remineralization for 18 days yielded a reduction in acid penetration depth and an increase in surface smoothness, which correlated with each other only for controls and treatment with New Metal Strips or Ortho-Strips.

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“…Few studies used measures of central tendency to report caries . These attempts used mean ICDAS, mean ICDAS in carious teeth and total ICDAS.…”

Section: Discussionmentioning

confidence: 99%

Caries reporting in studies that used the International Caries Detection and Assessment System: A scoping review

ElSalhy

Ali

Lai

et al. 2018

Comm Dent Oral Epid

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Objective To explore how caries was reported in studies that employed the International Caries Detection and Assessment System (ICDAS). Methods A systematic database search up to August 2017 was carried out using PubMed, Ovid MEDLINE, Cochrane library and ISI Web of Science electronic databases. Only studies that used the ICDAS for dental caries examinations were included. Studies were excluded if the examination was done only for the validation or the calibration of the ICDAS and/or if the examination was not done for the whole dentition. Measures used to report caries were considered. Results A total of 126 papers met the inclusion criteria. Forty‐four different synthesis measures were used to report caries. Most of the studies used a combination of multiple measures to report patient's caries level. These reporting measures cluster into four main groups: the number of individual ICDAS scores (ie, total counts of every score); the number of decayed surfaces/teeth (ie, total counts of combined caries scores for surfaces or teeth); measures of caries experience (ie, total counts of combined caries scores, filled and/or missing surfaces or teeth); and measures of central tendency and dispersion. The number of decayed surfaces and individual ICDAS scores were the most commonly used measures. Three studies used mean ICDAS score (ie, total ICDAS scores divided by the number of teeth), two used mean ICDAS score of carious teeth (ie, total ICDAS scores divided by the number of carious teeth) and two used the maximum ICDAS score (ie, highest ICDAS score recorded). The total ICDAS score was used only once. Many studies synthesized from the ICDAS the number of decayed, missing and filled teeth/surfaces (dmft/DMFT, dmfs/DMFS) as a measure of caries experience. Conclusions There are variations among studies in the utilization of the system to summarize caries. Most studies presented caries data using the categorical characteristics of the ICDAS.

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Efficacy of fluoride varnish for preventing white spot lesions and gingivitis during orthodontic treatment with fixed appliances—a prospective randomized controlled trial

Abstract: In dental practice, patients often receive an application of fluoride varnish at the start of orthodontic treatment with fixed appliances. However, the efficacy of this procedure is still unclear.

Cited by 53 publications

References 23 publications

Impact of a non‐fluoridated microcrystalline hydroxyapatite dentifrice on enamel caries progression in highly caries‐susceptible orthodontic patients: A randomized, controlled 6‐month trial

Impact of a non‐fluoridated microcrystalline hydroxyapatite dentifrice on enamel caries progression in highly caries‐susceptible orthodontic patients: A randomized, controlled 6‐month trial

Depth of acid penetration and enamel surface roughness associated with different methods of interproximal enamel reduction

Caries reporting in studies that used the International Caries Detection and Assessment System: A scoping review

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