Efficacy of Fluconazole at a 400 mg Weekly Dose for the Treatment of Onychomycosis

Hryncewicz-Gwóźdź, Anita; Plomer-Niezgoda, Ewa; Kalinowska, Katarzyna; Czarnecka, Anna; Maj, Joanna; Jagielski, Tomasz

doi:10.2340/00015555-1913

Cited by 4 publications

(2 citation statements)

References 9 publications

(12 reference statements)

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“…Of the 302 PubMed initial search results, 182 clinical trials (28,352 participants) met inclusion criteria and were included in the final analysis 6–186 . The PRISMA study selection process is detailed in Figure 1.…”

Section: Resultsmentioning

confidence: 99%

Race reporting and representation in onychomycosis clinical trials: A systematic review

Chang

Qiu

Lipner

2021

Mycoses

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Onychomycosis is the most common nail disorder seen in clinical practice with a prevalence of 8.7%-13.8% in the United States (US). [1][2][3] There has been a trend towards increased racial and ethnic diversity in the United States, with current projections estimating that minority representation will exceed 50% of the population by 2044. 4 Demographic reporting and inclusion of diverse populations within clinical trials is critical to interpret treatment efficacy and prognosis for different groups. A systematic review on racial/ ethnic reporting of dermatology clinical trial participants has been performed, 5 but similar data from onychomycosis clinic trials have not been studied. Our objectives were to systematically review racial/ethnic reporting and representation, as well as, outcomes by race/ethnicity in onychomycosis clinical trials. | MATERIAL S AND ME THODSPubMed was searched in August 2020 for all peer-reviewed, Englishlanguage onychomycosis clinical trials. The keyword 'onychomycosis' was searched with no date ranges, article type filtered for 'Clinical

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Section: Resultsmentioning

confidence: 99%

Race reporting and representation in onychomycosis clinical trials: A systematic review

Chang

Qiu

Lipner

2021

Mycoses

View full text Add to dashboard Cite

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“…Pilot study 11 Toenail of fingernail [ [10][11][12][13][14][15][16]. The diffusion of the drug into the distal part of the nail occurs via nail bed that is further confirmed due to the presence of two foldhigher drug concentration in subungual nail material than in distal nail clippings of a patient treated for one month.…”

Section: Second Generation Oral Antifungalsmentioning

confidence: 99%