Efficacy of ethyl ascorbyl ether–containing cosmetic cream on blue light–induced skin changes

Jo, Hong Li; Jung, Yuchul; Kim, Young Kyun; Kim, Nahee; Cho, Eunbyul; Han, Jiyeon; Hwang, Yoon Kyun; Suh, Byung‐Fhy; Kim, Eun-Joo

doi:10.1111/jocd.14232

Cited by 6 publications

(7 citation statements)

References 16 publications

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“…When considering cosmetic interventions for protecting against blue light, a strategy of daytime protection and night-time repair may be optimal. An ideal regimen of daytime protection would include reduced exposure to blue light and prevention or minimization of free radical formation (Table 4) [22,34,[46][47][48][49][50][51]. An ideal regimen of night-time repair would include greater protection of the opsin photoreceptors against activation, collagen against degradation, mitochondria against damage, and DNA against oxidation, as well as other methods (Table 4) [11,29,[51][52][53][54][55][56][57][58][59][60][61].…”

Section: Indirect Effects Of Blue Lightmentioning

confidence: 99%

Direct and Indirect Effects of Blue Light Exposure on Skin: A Review of Published Literature

Suitthimeathegorn

Cheng

et al. 2022

Skin Pharmacol Physiol

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The growing use of electronic devices and other artificial light sources in recent decades has changed the pattern of exposure to blue light (400–500 nm). Although some progress has been made in the study of the biological effects of blue light on the skin, many questions in this field remain unexplored. The aim of this article was to review the currently available evidence on the deleterious effects of blue light on the skin, as well as the methods and strategies designed to protect from the detrimental effects of blue light. PubMed and ProQuest databases were searched in January 2022. Search results were supplemented by articles considered relevant by the authors. The results of in vitro, in vivo and clinical studies show that blue light produces direct and indirect effects on the skin. The most significant direct effects are the excessive generation of reactive oxygen and nitrogen species, and hyperpigmentation. Reactive oxygen and nitrogen species cause DNA damage and modulate the immune response. Indirect effects of blue light include disruption of the central circadian rhythm regulation via melatonin signaling and local circadian rhythm regulation via direct effects on skin cells. Antioxidants and sunscreens containing titanium dioxide, iron oxides, and zinc oxide can be used to protect against the detrimental effects of blue light as part of a strategy that combines daytime protection and night-time repair. Blue light produces a wide variety of direct and indirect effects on the skin. As exposure to blue light from artificial sources is likely to continue to increase, this area warrants further investigation.

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Section: Indirect Effects Of Blue Lightmentioning

confidence: 99%

Direct and Indirect Effects of Blue Light Exposure on Skin: A Review of Published Literature

Suitthimeathegorn

Cheng

et al. 2022

Skin Pharmacol Physiol

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“…Moreover, LED lights are present in a plethora of products that come into contact with the skin, including lamps for indoor and outdoor illumination, medical indications, and lamps used in extremity care facilities [11,[16][17][18]. In addition, the maximum emission range for televisions and computer monitors is between 400 and 490 nm [19], whereas the range for tablets and smartphones is between 452 and 456 nm [20].…”

Section: Blue Light Sourcesmentioning

confidence: 99%

“…The most powerful television displays have a blue light irradiance of 30 µW/cm 2 , according to a report by Passeron's group [23]. In their work, Jo et al [20] calculated the daily dose of blue light exposure using measurements of sunshine taken in March 2019 and August 2019, and the result was 38,790 J/cm 2 . The computed dose of blue light exposure indoors, excluding sunlight, was 6993 J/cm 2 .…”

Section: Recent Data On Light Exposurementioning

confidence: 99%

“…More specifically, the dose of fluorescent lamps was calculated at 6.529 J/cm 2 /day, from computer screens at 0.383 J/cm 2 , from televisions at 0.022 J/cm 2 , from tablets at 0.031 J/cm 2 , and from mobile cell phones at 0.029 J/cm 2 . Based on the above data, Jo et al concluded that individuals are frequently subjected to blue light, mainly from sunlight during outdoor activities but also from digital devices during indoor activities [20].…”

Section: Recent Data On Light Exposurementioning

confidence: 99%

“…The recent increase in the use of modern technology has led to various types of electrical devices emitting electromagnetic fields in both the home environment and the workplace [3]. It has been reported that an office worker's typical exposure is 1597 J/cm 2 over approximately 27 days, 958 J/cm 2 over approximately 16 days, and 447 J/cm 2 over approximately 8 days [20]. Recent reports have shown a rapid increase in the use of smartphones and electronic devices in general during the COVID-19 pandemic [25].…”

Section: Recent Data On Light Exposurementioning

confidence: 99%

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Deciphering the Effects of Different Types of Sunlight Radiation on Skin Function: A Review

Letsiou,

Koldiri,

Beloukas

et al. 2024

Cosmetics

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Sunlight radiation is a fundamental component of our daily lives. Specifically, blue light as well as UV light appear to play a role in the development of oxidative stress, DNA damage, photoaging, and pigmentation through the chromophores in skin tissues. However, several skin problems like psoriasis, eczema, and atopic dermatitis can be avoided with short-duration exposures to low-energy blue light radiation or UV radiation. In addition, exploring the effects of blue light as well as UV radiation on skin is quite essential for the development of minimally invasive antiaging strategies and for the design of innovative cosmetic formulations in modern aesthetics and cosmetology. Thus, in this review, we present the advantages as well as the disadvantages of light radiation, with a special focus on blue light and UV radiation activity on the human skin. We also discuss the molecular action of blue light and UV radiation on human skin. Other types of light radiation are included to holistically approach the effect of light on human skin.

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Highlighting nuances of blue light phototherapy: Mechanisms and safety considerations

Uzunbajakava

Tobin

Botchkareva

et al. 2022

Journal of Biophotonics

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The efficacy of blue light therapy in dermatology relies on numerous clinical studies. The safety remains a topic of controversy, where potentially deleterious effects were derived from in vitro rather than in vivo experiments. The objectives of this work were (1) to highlight the nuances behind “colors” of blue light, light propagation in tissue and the plurality of modes of action; and (2) to rigorously analyze studies on humans reporting both clinical and histological data from skin biopsies with focus on DNA damage, proliferation, apoptosis, oxidative stress, impact on collagen, elastin, immune cells, and pigmentation. We conclude that blue light therapy is safe for human skin. It induces intriguing skin pigmentation, in part mediated by photoreceptor Opsin‐3, which might have a photoprotective effect against ultraviolet irradiation. Future research needs to unravel photochemical reactions and the most effective and safe parameters of blue light in dermatology.

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Efficacy of ethyl ascorbyl ether–containing cosmetic cream on blue light–induced skin changes

Cited by 6 publications

References 16 publications

Direct and Indirect Effects of Blue Light Exposure on Skin: A Review of Published Literature

Direct and Indirect Effects of Blue Light Exposure on Skin: A Review of Published Literature

Deciphering the Effects of Different Types of Sunlight Radiation on Skin Function: A Review

Highlighting nuances of blue light phototherapy: Mechanisms and safety considerations

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