Efficacy of early treatment of facial port wine stains in newborns: A review of 49 cases

Abstract

Frequent, high energy pulsed-dye laser treatments are safe and highly effective in improving facial PWS in infants < or =6 months of age. Patients with PWS should be referred for pulsed-dye laser treatment during early infancy.

Management of vascular lesions using advanced laser technology

“…These are mostly observed in older patients and their treatment may be particularly difficult in many cases due to the greater depth of the vascular lesion [35,36] . The treatment of PWS using lasers is more effective when conducted during the first year after birth, which can partly be explained by the fact that the infant's skin is thinner, allowing greater penetration of the laser [37] . During the subsequent stages of PWS's development, treatment is not effective and sometimes resistance to treatment is observed.…”

“…In general, however, PWS on the face tend to respond better to the treatment than lesions on the rest of the body [45] . As a whole, the treatment of congenital vascular lesions using laser has been proven to be effective when initiated during the first year of life, something that is partially explained by the fact that the infant's skin is thinner and better penetration of the laser beam within the lesion is achieved [37] . PDL remains the first treatment of choice for most patients with PWS, with desired clinical endpoint being light purpura presented immediately or within a few minutes post-treatment.…”

Perioküler Bölge Hemanjiyomlarının Tedavisinde Güncel Yaklaşımlar

“…Pulsed dye laser uygulaması özellikle 1 yaş altı olgularda oldukça başarılı olabilen bir tedavi yöntemidir. 28 Bu başarı hasta büyüdükçe ve ciltte kabalaşma başladıkça azalır. 28 Ayrıca laser tedavisiyle kombine olarak uygulanan topikal imikomodun (Aldara %5 Krem, Meda Pharma İlaç) lezyon rengindeki açılmaya yardımcı olduğu da bildirilmiştir.…”

“…28 Bu başarı hasta büyüdükçe ve ciltte kabalaşma başladıkça azalır. 28 Ayrıca laser tedavisiyle kombine olarak uygulanan topikal imikomodun (Aldara %5 Krem, Meda Pharma İlaç) lezyon rengindeki açılmaya yardımcı olduğu da bildirilmiştir. 29 Eşlik eden sekonder glokom, refraksiyon kusurları ve ambliyopi tedavisi mutlaka uygulanmalıdır.…”

Current treatment options for port wine stain birthmarks

“…Light dosing was more difficult and scarring more common in those under 5. This is in contrast to PDL therapy, where the greatest lesion lightening has been reported in young patients [3]. Further research is required, but perhaps PDL treatment is optimal when therapy is begun in those under 5 years, with PDT being an option for those 5 and older.…”