Efficacy of Disinfectants in Inactivating H5N1 Avian Influenza Virus in Poultry Feces

Abstract

Avian Influenza virus subtype H5N1 is widely distributed among all over the world and is very important from public health, animal health and economic point of view. The virus is excreted in high concentrations in secretions and excretions including feces. It is transmitted by direct contact or indirectly through contaminated feed and water or fecal material carried through personnel and equipments. This study was carried out to check the efficacy of different disinfectants to inactivate the H5N1 virus. Efficacy of three disinfectants including ethanol (70%), NaOH (1% and 2%), and a commercial disinfectant, D125® at different dilutions were tested in inactivating the Indian H5N1 virus in poultry feces. Efficacy of disinfectants was determined by comparing the reduction in percent infectivity of virus to embryonated chicken eggs in test group and control group. The study indicated that all three disinfectants were able to inactivate the virus but their efficiency was primarily dependent on concentrations and contact time. Out of the studied disinfectants, it can be concluded that 70% ethanol, 2% NAOH and D125® (1:32 concentration) can effectively be used in laboratory and field conditions.All copyrights reserved to Nexus® academic publishers

Ultra violet light in the Biosafety Cabinets fails to inactivate H5N1 Avian Influenza Virus in Poultry Feces

“…Proper cleaning of BSCs before and after handling of infected feces should be done. Disinfectants like 70% ethanol can effectively be used in laboratory (Kurmi et al, 2014). …”