Efficacy of different protocols of vaccination against porcine circovirus type 2 (PCV2) in a farm affected by postweaning multisystemic wasting syndrome (PMWS)

Mixed treatment comparison meta-analysis of porcine circovirus type 2 (PCV2) vaccines used in piglets

“…It was not possible to determine with confidence the correct degrees of freedom to calculate the SEM of treatment level ADG. Pejsak et al (2010) It is not a controlled trial. Reindl et al (2010) Poor report not enough information for control.…”

Association of concurrent porcine circovirus (PCV) 2a and 2b infection with PCV associated disease in vaccinated pigs

“…The current commercially available vaccines are widely considered as highly effective in inducing protective immunity against PCVAD under field conditions Kixmöller et al, 2008;Segalés et al, 2009;Pejsak et al, 2010). Three of these vaccines are subunit vaccines based on the PCV2 capsid protein expressed in baculovirus including Ingelvac CircoFLEX Ò (Boehringer Ingelheim), Circumvent Ò PCV M (Merck Animal Health, Inc) and Porcilis Ò PCV (MSD Animal Health).…”

A commercial PCV2a-based vaccine significantly reduces PCV2b transmission in experimental conditions

“…From 2006, commercial vaccine solutions were made available on the market. Based on different principles (inactivated PCV2, PCV2 capsid protein produced in a vector or chimeric inactivated PCV1 virus including PCV2 ORF2), the efficacy of those vaccines, prepared with strains of PCV2a genogroup, has been described in several experimental [5] or field studies [6][7][8][9][10][11]. Generally, commercial vaccines have been shown to reduce viraemia, viral load in tissues and lymphoid lesions [12][13][14].…”