Efficacy of Dietary Zinc Oxide Nanoparticles Supplementation on Serum Biochemical, Nutrients Retention and Chemical Composition of Meat and Tibia in Broiler Chickens

Abstract

A total of 192 unsexed day-old "Cobb" broiler chicks were used to evaluate the effects of different levels of dietary nano zinc oxide (N-ZnO) on nitrogen and minerals retention, blood serum measurements, meat chemical composition and tibia minerals of broiler chickens. Chicks were randomly distributed into six treatments of four replicates eight chicks each. A control contained 100 mg inorganic ZnO/kg diet (I-ZnO) and 100, 80, 60, 40 and 20 mg N-ZnO/kg diet were fed. Diets supplemented with different levels of N-ZnO had significant effect on blood serum parameters except for total protein and cholesterol. The highest contents of (albumin, high density lipoprotein, low-density lipoprotein, lactate dehydrogenase, superoxide dismutase, calcium, phosphorous and zinc) and the lowest (triglycerides, creatinine, uric acid, aspartate transferase, alanine transferase, alkaline phosphatase and malondialdehyde) were obtained with 20 mg N-ZnO/kg diet. A significant reduction in moisture and fat and significant increase in crude protein, ash and minerals (Ca, P and Zn) of breast and thigh meats were observed with N-ZnO treatments; the lowest and the highest percentages, respectively, of the former criteria were recorded with 20 mg N-ZnO. Birds fed N-ZnO (40 and 20), (60, 40 and 20) and 20 mg/kg diet had the highest significant tibia Ca, Zn and P percentages, respectively. Nano-ZnO treatments significantly increased the retention percentages except for Zn. Birds fed 40 mg N-ZnO/kg diet exhibited the highest nitrogen, Ca, P and Zn retention. It could be concluded that supplementation of N-ZnO to broiler diet improved birds' physiological status, meat carcass quality, bone mineralization and nutrients retention. The lower levels of N-ZnO (20 and 40 mg/kg diet) revealed promising results with no harmful effect on birds' health status.

Effects of dietary supplementation of myco-fabricated zinc oxide nanoparticles on performance, histological changes, and tissues Zn concentration in broiler chicks

“…In similar direction, serum total cholesterol and TG decreased significantly and activities of liver enzymes (AST and ALT) remained unchanged in the serum of Japanese quail fed ZnONPs at 30 or 60 mg/kg compared to the control 39 . Current results also came in accordance with Attia and co-workers who recorded a reduction in cholesterol, TG, creatinine, uric acid and increased HDL with the supplementation of ZnONPs at level of 20 or 40 mg/kg diet 40 . Moreover, these observations were attributed to the ability of Zn to induce glucagon secretion and suppress insulin secretion 41 .…”