Efficacy of Dequalinium Chloride vs Metronidazole for the Treatment of Bacterial Vaginosis
Grzegorz Raba,
Anton Ďurkech,
Tomáš Malík
et al.
Abstract:ImportanceBacterial vaginosis (BV) is a common cause of vaginal infection. First-line treatments of BV are metronidazole and clindamycin. Due to the increase in antibiotic resistance, effective nonantibiotic treatments for BV are needed.ObjectiveTo examine whether dequalinium chloride, a broad-spectrum antiseptic, is noninferior to oral metronidazole for the treatment of BV.Design, Setting, and ParticipantsThis phase 4, multicenter, triple-blind, double-dummy, parallel, noninferiority randomized clinical trial… Show more
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