Efficacy of Crude Extract from Streptomyces cellulosae Against Biofilm-Related Genes of Candida albicans
Chiman Hamarahim Fattah,
Khattab Ahmed Mustafa Shekhany,
Shwan Rachid
Abstract:Background: Candida albicans (C. albicans) is notably pathogenic due to its ability to form biofilms that are resistant to conventional antifungal treatments. Objectives: This study aims to explore the effectiveness of Streptomyces cellulosae (S. cellulosae) extract in disrupting biofilm formation by targeting specific genes within C. albicans. Methods: The study began by isolating S. cellulosae from soil and C. albicans from clinical specimens. S. cellulosae was then cultured and fermented to produce bioactiv… Show more
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