Efficacy of continuous infusion of Mannitol during cardiopulmonary bypass in Minimally Invasive Cardiac Surgery

Abstract

Objective：During cardiopulmonary bypass(CPB)on Minimally Invasive Cardiac Surgery(MICS) ，there are few reports that gave Mannitol of CPB continuously, and the clinical response is not clear. The aim of this study is to inspect influied balance in the perioperative period by giving Mannitol in CPB continuously and influence on oxygenicity. Method：We collected 84 CPB cases which went by MICS from November, 2012 to December, 2014. The detail of it, 39 cases after September, 2013 were the things which we gave Mannitol to continuously(C group) ，and, 45 cases before September, 2013 did not use Mannitol continuously(nonC group) ． Results：The urine until 12 hours after an operation from all over the operation and balance growth rate(IBGR)during CPB were no significant. However, the IBGR significantly recognized improvement after during the operation and an operation in C group over 12 hours. After distributing two groups according to renal function more, IBGR rose in RF group, but tended IBGR was improved in C group. Also A-aDO2 and P/F ratio were no significant between C group and the nonC group, but P/F ratio significantly relates to IBGR. Conclusions：Efficacy of continuous infusion of Mannitol during extracorporeal circulation is control IBGR, and it may also prevent postoperative respiratory complications in MICS. Key words：mannitol，minimally invasive cardiac surgery(MICS) ，influied barance，peri operative