Efficacy of Combination Use of Beta-Lactamase Inhibitor with Penicillin and Fluoroquinolones for Antibiotic Prophylaxis in Transrectal Prostate Biopsy

Shigemura, Katsumi; Matsumoto, Minori; Tanaka, Kazushi; Yamashita, Masuo; Arakawa, Soichi; Fujisawa, Masato

doi:10.4111/kju.2011.52.4.289

Cited by 14 publications

(7 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, other studies from North America [12,13] reported lower rates of sepsis (0.6%), and an Asian study [14] reported that 0.5% of prostate biopsy cases had fever, similar to the data of our study.…”

Section: Discussionsupporting

confidence: 91%

Characteristics of Patients Who Visited the Emergency Room after Prostate Biopsy: Single Center Retrospective Study

Jeong

Lee

Chung

2015

Urogenit Tract Infect

View full text Add to dashboard Cite

Purpose: To educate patients and prevent biopsy-related complications, it is helpful to understand the causes for visiting the emergency room (ER).Therefore, we want to analyze the causes and factors of complications that cause patients to visit the ER after prostate biopsy. Materials and Methods:We conducted a study of in-patients who visited the ER of Pusan National University Yangsan Hospital after prostate biopsy from December 2008 to July 2015. Age, postoperative interval before visiting the ER, Charlson comorbidity index (CCI) score, symptoms in ER, prostate size, pathologic result, and number of biopsy cores were analyzed retrospectively. Results: Among all 1,694 cases of patients who had undergone prostate biopsies during a 7-year period, only 37 patients (2.2%) visited the ER. Diabetes mellitus (DM) is the most common underlying disease among patients with accompanying infection-related symptoms compared to patients with accompanying non-infection-related symptoms (p＜0.001). In univariate analysis, DM (p=0.004) and CCI score (p=0.030) were statistically significant risk factors for infection, but only DM was significant in multivariate analysis (p=0.004). Prostate size (p=0.044) was a significant risk factor for acute urinary retention (AUR) in univariate analysis, but not statistically significant in multivariate analysis. CCI score was a statistically significant risk factor for bleeding (p=0.005 [univariate], 0.035 [multivariate]). Conclusions: AUR after transrectal ultrasound-biopsy is the most common reason for visiting the ER. CCI score showed correlation with bleeding and DM showed correlation with infection. Consideration of risk factors of complications after prostate biopsy will be helpful to the patients in the treatment and prevention of complication.

show abstract

Section: Discussionsupporting

confidence: 91%

Characteristics of Patients Who Visited the Emergency Room after Prostate Biopsy: Single Center Retrospective Study

Jeong

Lee

Chung

2015

Urogenit Tract Infect

View full text Add to dashboard Cite

show abstract

“…13 In the present study, we could not perform any temporal analyses of complications because the length of the study was insufficient; to the best of our knowledge, there have been no such temporal analyses in Hong Kong. The infection rate in our cohort was comparatively lower than that of most international studies, 4 and similar to that in prior studies elsewhere in Asia 14,15 (0% and 0.5% of PBI), as well as in Hong Kong 5,6 (0.5% and 3.9%). Reasons for the apparent lower infection rate in people of Asian ethnicity compared with those of other ethnicities are unclear.…”

Section: Infective Complicationssupporting

confidence: 87%

Emergency attendances and hospitalisations for complications after transrectal ultrasound-guided prostate biopsies: a five-year retrospective multicentre study

et al. 2019

View full text Add to dashboard Cite

Transrectal ultrasound-guided (TRUS) prostate biopsy is an established procedure for diagnosis of prostate cancer. Complications after TRUS biopsy are not well reported in Hong Kong. This study evaluated the 5-year incidences of TRUS biopsy complications and potential risk factors for those complications. Methods: This was a retrospective review of biopsies performed from 2013 to 2017 in two local hospitals, using data retrieved from electronic medical records. The primary outcome was the occurrence of complications requiring either emergency attendances or hospitalisations within 30 days after biopsy. Potential risk factors were examined using multiple logistic regression analysis. Results: In total, 1699 men were included (mean age ± standard deviation: 67 ± 7 years; median prostatespecific antigen level: 7.9 µg/L [interquartile range, 5.5-12.6 µg/L]); 4.3% had pre-biopsy bacteriuria. Overall, 5.7% and 3.8% of post-biopsy complications required emergency attendances and hospitalisations, respectively. Gross haematuria and rectal bleeding requiring emergency attendances developed in 2.1% and 0.4% of men; 0.8% and 0.4% required hospitalisations. Furthermore, 1.5% of men developed acute urinary retention requiring hospitalisations; 1.9% and 1.2% had post-biopsy infections requiring emergency attendances and

show abstract

“…Taken together, AMP with a single high dose of quinolones is recommended for low‐risk patients who are undergoing a transrectal prostate biopsy (EL, II; RG, B). Additionally, a combination of aminoglycosides with quinolones or tazobactam/piperacillin can reduce the rate of infection, and is considered to be an optional selection (EL, IVa; RG, C1). As for AMP for high‐risk patients who have a large prostate volume of 75 mL or more, diabetes, steroid dosing, voiding dysfunction (IPSS ≥20, maximum urinary flow rate ≤12 mL/s, residual volume ≥100 mL) or immune‐suppression status, tazobactam/piperacillin at 4.5 g, twice for a single day is recommended (EL, III; RG, B) …”

Section: Detailed Exposition 8: Prostate Biopsymentioning

confidence: 99%

Essential Japanese guidelines for the prevention of perioperative infections in the urological field: 2015 edition

Yamamoto

Shigemura

Kiyota³

et al. 2016

Int J of Urology

Self Cite

View full text Add to dashboard Cite

After publication of the initial version of the Japanese guidelines for urological surgery in 2007, new surgical techniques have been introduced. Furthermore, several important issues, such as criteria for use of single-dose antimicrobial prophylaxis and control of hospitalized infection, were also established, which led to alterations of the methods used for antimicrobial prophylaxis as well as perioperative management. The purpose of antimicrobial prophylaxis is to protect the surgical wound from contamination by normal bacterial flora. Antimicrobial prophylaxis should be based on penicillins with beta-lactamase inhibitors, or first-or second-generation cephalosporins, though penicillins without beta-lactamase inhibitors should not be prescribed because of the high prevalence of antimicrobial resistance. As an adequate intratissue concentration of the antimicrobial at the surgical site should be accomplished by the time of initiation of surgery, antimicrobial prophylaxis should be started up to 30 min before beginning the operation. Antimicrobial prophylaxis should be terminated within 24 h in clean and clean-contaminated surgery, and within 2 days of surgery using the bowels, because a longer duration is a risk factor for surgical site infection development. Importantly, possible risk factors for surgical site infections include the antimicrobial prophylaxis methodology used as well as others, such as duration of preoperative hospitalization, hand washing, the American Society of Anesthesiologists score, diabetes and smoking history. These guidelines are to be applied only for preoperatively non-infected low-risk patients. In cases with preoperative infection or bacteriuria that can cause a surgical site infection or urinary tract infection after surgery, patients must receive adequate preoperative treatment based on the individual situation.

show abstract

Efficacy of Combination Use of Beta-Lactamase Inhibitor with Penicillin and Fluoroquinolones for Antibiotic Prophylaxis in Transrectal Prostate Biopsy

Cited by 14 publications

References 19 publications

Characteristics of Patients Who Visited the Emergency Room after Prostate Biopsy: Single Center Retrospective Study

Characteristics of Patients Who Visited the Emergency Room after Prostate Biopsy: Single Center Retrospective Study

Emergency attendances and hospitalisations for complications after transrectal ultrasound-guided prostate biopsies: a five-year retrospective multicentre study

Essential Japanese guidelines for the prevention of perioperative infections in the urological field: 2015 edition

Contact Info

Product

Resources

About