Efficacy of Cloprostenol and Cabergoline Therapy in Cystic Endometrial Hyperplasia – Pyometra Complex Bitches

Meher, J.; Patil, A; Sahatpure, S. K.; Bhojne, G. R.; Patil, D. B.

doi:10.29005/ijcp.2018.10.1.024-028

Cited by 2 publications

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“…However, it decreased significantly (p<0.01) faster (on day 7) in both the hormonal treated groups (T 1 and T 2 ) as compared to non-hormonal treatment (Tc) group. Similar results on uterine diameter were also reported using different treatment in canine pyometra by Renukaradhya (2011) and Meher et al (2018). The several studies supporting the procedure adopted in this study for the confirmation of pyometra as the diagnosis of pyometra is best made with the aid of ultrasonography (Bigliardi et al, 2004) and findings typically include an enlarged uterus with convoluted, tubular horns filled with anechoic to hypoechoic fluid (Plate 1) (Fayrer-Hosken et al, 1991 andVoges et al, 1996).…”

Section: Effect Of Different Treatment Regimens On Total Uterine Diam...supporting

confidence: 84%

“…Neutrophilia has also been reporded in several studies (Hagman et al, 2006;Renukaradhya, 2011 andArunima, 2013). It might be due to retention of purulent exudates in the uterus which exerts a chemotactic effect on neutrophils resulting into accelerated granulopoiesis (Meher et al, 2018). The neutrophilia recorded in the present investigation may be attributed to the defense mechanism of the uterus in response to the invading microorganisms.…”

Section: Effect Of Different Treatment Regimens On Total Uterine Diam...mentioning

confidence: 53%

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Therapeutic Response of Mifepristone with Dinoprost and Misoprostol for Management of Canine Pyometra

Kumar

Shukla

Kumar

et al. 2021

IJAR

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Background: Canine pyometra (chronic purulent endometritis) is one of the most important uterine disorder of bitches seeks medical treatment. The hormonal therapies are not much popular among the veterinarians thus needs to exploit some hormonal protocols for this condition. Therefore, the experiment was carried out to study the therapeutic response of antiprogestin and prostaglandin in canine pyometra. Methods: The experiment was carried out in total 21 bitches affected with pyometra were selected and divided randomly into 3 groups. Animals of control group (TC) were treated with non-hormonal supportive treatment for 7 days. Animals of T1 were received non-hormonal supportive treatment for 7 days similar to TC along with mifepristone @ 3 mg/kg orally BID on day 1, 2 and 8 and Dinoprost in @ 50-200 mcg/kg S/C day 3 to 7. Animals of T2 were treated similar to TC plus mifepristone @ 3 mg/kg orally BID on day 1, 2 and 8 and Misoprostol @ 3 mcg/kg intravaginally twice daily on day 3 to 7. Result: Therapeutic responses was recorded better in T1 group (100%), followed by T2 (71.43%) and TC (42.86%). The mean TLC values after completion of treatment (day 8) were significantly decreased in T1 and T2. The neutrophil count in different groups T1, T2 and TC was reduced significantly. There was significant decrease in mean concentration of BUN and creatinine on day 8 after treatment in T1 and T2 groups. The mean ALT values decreased significantly in T1 group. However, ALP values decreased significantly in T1 and T2 groups. The mean serum progesterone declined significantly in both the hormone treated groups (T1 and T2). The study can be concluded that therapeutic response of mifepristone with dinoprost tromethamine was found most effective for the treatment of canine pyometra than mifepristone with misoprostol protocol.

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Section: Effect Of Different Treatment Regimens On Total Uterine Diam...supporting

confidence: 84%

Section: Effect Of Different Treatment Regimens On Total Uterine Diam...mentioning

confidence: 53%

Therapeutic Response of Mifepristone with Dinoprost and Misoprostol for Management of Canine Pyometra

Kumar

Shukla

Kumar

et al. 2021

IJAR

View full text Add to dashboard Cite

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Canine Pyometra: Efficacy of Different Therapeutic Protocols on Blood Count and Serum Biochemistry

Pitroda,

Singh,

Kumar

et al. 2024

Preprint

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Efficacy of Cloprostenol and Cabergoline Therapy in Cystic Endometrial Hyperplasia – Pyometra Complex Bitches

Cited by 2 publications

References 0 publications

Therapeutic Response of Mifepristone with Dinoprost and Misoprostol for Management of Canine Pyometra

Therapeutic Response of Mifepristone with Dinoprost and Misoprostol for Management of Canine Pyometra

Canine Pyometra: Efficacy of Different Therapeutic Protocols on Blood Count and Serum Biochemistry

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