Efficacy of bovine viral diarrhea virus vaccination to prevent reproductive disease: A meta-analysis

Newcomer, Benjamin W.; Walz, Paul H.; Givens, M. Daniel; Wilson, Alan E.

doi:10.1016/j.theriogenology.2014.09.028

Cited by 69 publications

(40 citation statements)

References 55 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Mean annual BVDV direct losses per animal were 8%–12% and 28%–29% lower in studies including vaccination and biosecurity as compared to studies omitting these mitigation measures, respectively (Table ). This result is in agreement with the meta‐analysis by Newcomer, Walz, Givens, and Wilson (). The study reveals that abortion decreased by 45% and the foetal infection rate decreased by approximately 85% in cattle herds vaccinated against BVDV compared with non‐vaccinated herds (Newcomer et al, ).…”

Section: Discussionsupporting

confidence: 92%

Epidemiological factors and mitigation measures influencing production losses in cattle due to bovine viral diarrhoea virus infection: A meta‐analysis

Pinior

Garcia

Minviel

et al. 2019

Transbound Emerg Dis

View full text Add to dashboard Cite

Infection with bovine viral diarrhoea virus (BVDV) is associated with a loss in productivity in cattle farms. Determining which factors influence monetary losses due to BVDV could facilitate the implementation of mitigation measures to reduce the burden of BVDV. Mixed‐effect meta‐analysis models were performed to estimate the extent to which the costs of mean annual BVDV production losses per animal may be influenced by epidemiological factors such as BVDV introduction risk, initial prevalence, viral circulation intensity and circulation duration (trial 1). Additionally, changes in mean annual BVDV production losses per animal due to specific mitigation measures (i.e., biosecurity, vaccination, testing and culling, cattle introduction or contact with neighbouring cattle herds) were analysed (trial 2). In total, 19 studies were included in the meta‐analysis to assess mean annual BVDV production losses. The mean annual direct losses were determined to be €42.14 per animal (trial 1). The multivariate meta‐regression showed that four of the previously mentioned epidemiological factors significantly influenced the mean annual BVDV production losses per animal. Indeed, the per animal costs increased to €67.19 when these four factors (trial 1) were considered as “high or moderate” compared to “low”. The meta‐regression analysis revealed that implementation of vaccination and biosecurity measures were associated with an 8%–12% and 28%–29% decrease in BVDV production losses on average, respectively, when simulated herds were compared with or without such mitigation measures (trial 2). This reduction of mean annual BVDV production losses per animal due to mitigation measures was partially counteracted when farmers brought new cattle on to farm or allowed contact with neighbouring cattle herds. The influencing mitigation factors presented here could help to guide farmers in their decision to implement mitigation strategies for the control of BVDV at farm level.

show abstract

Section: Discussionsupporting

confidence: 92%

Epidemiological factors and mitigation measures influencing production losses in cattle due to bovine viral diarrhoea virus infection: A meta‐analysis

Pinior

Garcia

Minviel

et al. 2019

Transbound Emerg Dis

View full text Add to dashboard Cite

show abstract

“…The optimal vaccine strategy has been greatly debated. A meta‐analysis on the efficacy of BVDV vaccination to prevent reproductive disease was conducted, which showed that foetal infection was decreased by over 80% with killed vaccine (Newcomer et al., ). Live vaccine was more efficient in foetal infection than killed vaccine.…”

Section: Discussionmentioning

confidence: 99%

“…Vaccination scenarios assumed that all herds used vaccination. The vaccine efficacy was assumed to be 80% (Newcomer, Walz, Givens, & Wilson, ), and the infection probability λ among vaccinated animals was consequently reduced by 80%. For culling, we assumed that animals were tested by RT‐PCR for adults or by antigen enzyme‐linked immunosorbent assay (ELISA) testing using ear notch samples for calves, and that positive PI animals were culled.…”

Section: Methodsmentioning

confidence: 99%

Evaluation of bovine viral diarrhoea virus control strategies in dairy herds in Hokkaido, Japan, using stochastic modelling

Sekiguchi

Presi²,

Omori

et al. 2017

Transbound Emerg Dis

View full text Add to dashboard Cite

SummaryBovine viral diarrhoea virus (BVDV) infection in cattle can result in growth retardation, reduced milk production, reproductive disorders and death. Persistently infected animals are the primary source of infection. In Hokkaido, Japan, all cattle entering shared pastures in summer are vaccinated before movement for disease control. Additionally, these cattle may be tested for BVDV and culled if positive.However, the effectiveness of this control strategy aiming to reduce the number of BVDV-infected animals has not been assessed. The aim of this study was to evalu-

show abstract

“…Los programas de vacunación tienen como objetivo aumentar la inmunidad en el hato, reducir el impacto de las manifestaciones clínicas de la enfermedad y la circulación viral (23). En el presente estudio se observó una variación en la frecuencia de anticuerpos en los hatos vacunados desde 0 hasta 90 %, mientras que la prevalencia observada en hatos no vacunados estuvo entre 0 y 83 % (p > 0,05).…”

Section: Discussionunclassified

Identificación de factores asociados con la exposición al virus de la diarrea viral bovina (VDVB) en terneras de hatos lecheros de la sabana de Bogotá

2017

View full text Add to dashboard Cite

ResumenEl virus de la diarrea viral bovina (VDVB) es un patógeno que afecta la salud bovina; produce signos clínicos como bronconeumonía, diarrea, teratogenia y pérdidas reproductivas. El objetivo del estudio fue determinar la seroprevalencia y algunos factores asociados con la exposición al VDVB en un total de 930 terneras provenientes de 31 hatos lecheros de la sabana de Bogotá. Los datos de los hatos se obtuvieron a través de una encuesta epidemiológica, así como la información individual de las terneras. Se utilizó una prueba de ELISA para la detección de anticuerpos contra VDVB p80. Los datos se analizaron con estadística de frecuencias, descriptiva, análisis univariado y con un modelo de regresión logística binaria en el que se evaluaron factores de confusión a través de la comparación entre los odds ratio (OR) crudos y ajustados. La seroprevalencia promedio de VDVB fue del 27,1 % (rango 0-90 %); adicionalmente, en el 83,9 % de los hatos se observaron anticuerpos contra VDVB. Los factores asociados con la exposición a VDVB fueron: 1) la edad en animales menores de 4 meses (OR = 4,9; IC 95 %: 2,52-9,56), 2) histórico de aborto de la madre (OR = 6,4; IC 95 %: 3,91-10,46; p = 0,001) y 3) la presentación histórica de diarrea (OR = 2,6; IC 95 %: 1,58-4,46; p = 0,010). Este estudio permitió confirmar la alta exposición al virus en los hatos e identificar de algunos factores asociados, lo cual contribuye al conocimiento de la epidemiología de la enfermedad.Palabras clave: anticuerpos, diarrea viral bovina, epidemiología, exposición viral, factores asociados, prevalencia. Identification of factors associated with exposure to bovine viral diarrhea virus (BVDV) in dairy-herd calves in the Bogotá savanna AbstractBovine viral diarrhea virus (BVDV) is a pathogen that affects bovine health; it produces clinical signs such as bronchopneumonia, diarrhea, teratogenicity, and reproductive losses. This study aimed to determine seroprevalence and some other factors associated with exposure to BVDV in a total of 930 calves from 31 dairy herds in the Bogotá savanna. The data of the herds, as well as individual information of the calves, were collected through an epidemiological survey. An ELISA test was used to detect antibodies to BVDV p80. Data were analyzed with frequency and descriptive statistics, univariate analysis, and a binary logistic regression model, in which confounding factors were evaluated through a comparison between crude and adjusted odds ratios (OR). The average seroprevalence of BVDV was 27.1% (range 0-90%); additionally, antibodies against

show abstract

Efficacy of bovine viral diarrhea virus vaccination to prevent reproductive disease: A meta-analysis

Cited by 69 publications

References 55 publications

Epidemiological factors and mitigation measures influencing production losses in cattle due to bovine viral diarrhoea virus infection: A meta‐analysis

Epidemiological factors and mitigation measures influencing production losses in cattle due to bovine viral diarrhoea virus infection: A meta‐analysis

Evaluation of bovine viral diarrhoea virus control strategies in dairy herds in Hokkaido, Japan, using stochastic modelling

Identificación de factores asociados con la exposición al virus de la diarrea viral bovina (VDVB) en terneras de hatos lecheros de la sabana de Bogotá

Contact Info

Product

Resources

About