Efficacy of aloe vera gel as an adjuvant treatment of oral submucous fibrosis

Alam, Sarwar; Azhar, Iqbal; Giri, Kolli Yada; Sadhasivam, Gokkulakrishnan; Natu, Subodh Shankar; Faisal, Mohammad; Agarwal, Anshita; Sharma, Hemlata

doi:10.1016/j.oooo.2013.08.003

Cited by 40 publications

(36 citation statements)

References 14 publications

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“…In relation to quality of life, they found that there was significant difference between the aloevera and placebo groups [22]. Amanat D et al, compared Alam S et al, (2013) Both rinses were more effective in relieving xerostomía-associated symptomatology in patients taking 3 or more medicines simultaneously.…”

Section: Risk Of Bias Across Individual Studiesmentioning

confidence: 99%

Clinical Effectiveness of Aloe Vera in the Management of Oral Mucosal Diseases- A Systematic Review

Nair¹

2016

JCDR

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Section: Risk Of Bias Across Individual Studiesmentioning

confidence: 99%

Clinical Effectiveness of Aloe Vera in the Management of Oral Mucosal Diseases- A Systematic Review

Nair¹

2016

JCDR

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“…15 In the above study aloe vera was used as an adjuvant therapy where as in our study tulasi is used as a main therapy for osmf. Besides this they employed invasive techniques (injections and surgery) where as our therapy needs no invasion.…”

Section: -13mentioning

confidence: 79%

Tulasi a magical herb and a boon for management of oral submucous fibrosis: a clinical study

2017

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Background: Plants are a good source of drugs in traditional and modern medicine. One among these plants is "tulasi" The queen of herbs" which is used in ayurveda for its diverse properties like antioxidant, analgesic, antiinflammatory, antidiabetic, and others. It belongs to labiate family and is the most sacred and valued in traditional culture of India. AIMS of the study was to evaluate the efficacy of Tulasi in the treatment of OSMF. Methods: The study included 20 individuals, females and males of age group 20-50yrs who visited the outpatient department who were diagnosed clinically as having OSMF, categorized according to pindborg's classification. Patients were asked to apply 500mg of Tulasi medicine paste (Tulasi powder mixed with glycerine) twice daily for 1month and were recalled for follow up every week for 1month. All the clinical parameters -mouth opening, burning sensation, pain with the lesion and others were evaluated and recorded in specially designed proforma. Results: Friedman test and wilcoxon signed rank test was used for statistical evaluation. Significant improvement with P value <0.05 was noticed in burning sensation, mouth opening and pain associated with the lesion. Conclusions: The study concludes that Tulasi can be used as a main treatment modality in the management of patients with OSMF.

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“…The group receiving Aloe vera had a significant improvement in most symptoms of OSMF (p<0.01) compared with the non-Aloe vera group, in both the medicational and surgical categories. In conclusion, Alam S. group suggested that Aloe vera gel is effective as an adjuvant in treatment of OSMF [20] .…”

Section: Aloe Vera Gel: Role Of An Immune Adjuvantmentioning

confidence: 86%