Efficacy of albendazole against Taenia multiceps larvae in experimentally infected goats

Afonso, Sónia; Neves, Luís; Pondja, Alberto; Macuamule, Cristiano; Mukaratirwa, Samson; Arboix, M.; Cristòfol, Carles; Capece, Bettencourt P.S.

doi:10.1016/j.vetpar.2014.09.020

Cited by 4 publications

(2 citation statements)

References 22 publications

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“…Chemotherapy could be applied only inmigration stages of the parasite. The efficacy of the antiparasitic drugs such as albendazole, fenbendazole, and praziquantel against cerebral coenurosis was supported by other studies too; for instance, one study was done by Afonso et al, (2014) in 2014 and he has shown the response of coenurosis to the combination of fenbendazole, praziquantel and albendazole at a dose of 10 mg/kg for 3 days is effective in treating early infection of T. multiceps larvae in goats. The Taeniasis in the definitive host such as dog and wild calids can be treated with praziquantel, epsiprantel, mebendazole, febantel and fenbendazole (Scala and Varcasia, 2006).…”

Section: Treatmentsmentioning

confidence: 89%

Cerebral Coenurosis in Small Ruminants: A Review

Abera

Wubit

Nejash

2016

J. Anim. Sci. Adv.,

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Cerebral coenurosis is an important disease affecting sheep and goat which causes significant economic losses in their production. Cerebral Coenurosis is caused by larval stage of taenia multiceps known as coenurus cerebralis. The aim of this paper is to review the general aspects of cerebral coenurosis in small ruminants' and highlight its economic and public health significance. Coenurosis occurs in worldwide and it is endemic in Ethiopia, especially in the highland area where sheep population is high. The life cycle is commonly happens between dog and small ruminants. The adult stage of this parasite inhabits the small intestine of dogs, foxes, coyotes and jackals; while larvae are found in the brain and spinal cord of intermediate hosts. When dog consume the brain containing coenurus cyst, cyst develop into taenia multiceps and then start to pass proglottid containing egg on pasture and intermediate hosts get infected when ingest eggs from pasture. Circling, Dullness, torticollis, loss of appetite, frequent bleating, separation from the flock, visual impairment, muscle tremors are the main clinical signs related with coenurusis. Diagnosis is mostly by necrosy while radiology, ultrasonography and CT can also be used. Treatment of choice is by surgical removal of the cyst or by aspiration of fluid from the cyst; also combination of Fenbendazole, praziquantel and albendazole is effective against migratory stage of the larvae. The disease causes great economic loss in small ruminant production. Human get infected with coenurosis if ingests an egg of the parasite accidentally. Regular anthelmintic treatment of dogs, correct disposal of sheep and goat brain are the main control method of coenurosis. The community should Control dog contact with pasture and have to properly dispose the brain of infected sheep and goats after slaughter; also they should keep their hygiene to prevent ingestion of T. multiceps eggs.

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Section: Treatmentsmentioning

confidence: 89%

Cerebral Coenurosis in Small Ruminants: A Review

Abera

Wubit

Nejash

2016

J. Anim. Sci. Adv.,

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“…Portanto, o melhor é prevenir a infecção. Segundo Afonso et al (2014) o albendazol é eficaz em cabras contra cistos de 2 meses de idade, de T. Multiceps para larva localizada em tecidos fora do cérebro. Quando possível, a remoção cirúrgica é a único tratamento disponível (Merbl et al, 2014 (Rissi et al, 2008).…”

Section: Tratamentounclassified

Aspectos epidemiológicos, clínicos e patológicos da cenurose

Rodrigues¹,

Alencar²,

Medeiros³

2016

Pubvet

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A cenurose é uma doença cosmopolita causada pelo estágio larval da Taenia multiceps conhecido como Coenurus cerebralis. Também chamada de torneio verdadeiro, a cenurose acomete com frequência pequenos ruminantes provocando a formação de cistos, principalmente no Sistema Nervoso Central (SNC). Os ruminantes e outros ungulados atuam como hospedeiros intermediários e se infectam ingerindo os ovos contendo as oncosferas que são liberados nas fezes dos hospedeiros definitivos representados pelos canídeos domésticos e selvagens. Teve por objetivo neste artigo apresentar uma abordagem sobre a cenurose, abrangendo aspectos epidemiológicos, clínicos, patológicos e profiláticos da doença.

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Nervous System

2022

Goat Medicine

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Efficacy of albendazole against Taenia multiceps larvae in experimentally infected goats

Cited by 4 publications

References 22 publications

Cerebral Coenurosis in Small Ruminants: A Review

Cerebral Coenurosis in Small Ruminants: A Review

Aspectos epidemiológicos, clínicos e patológicos da cenurose

Nervous System

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