Efficacy of a two-component compression system for the therapy of venous leg ulcers

Escaleira, Ribeiro; Cardoso, Manuel Esteves; Rego, Julio Oscar Cabrera; Macedo, Priscila Marques de; Midões, Alberto

doi:10.12968/jowc.2010.19.3.47279

Cited by 13 publications

(9 citation statements)

References 12 publications

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“…The same search, as previously described, allowed us to retrieve nine publications reporting on time to wound closure (either mean or median) varying from 5 to 6 weeks up to 1 year. 32,36,40,53,[57][58][59][60][61] The BioPhotonic System performed well when compared with other treatments in terms of closure rates and time to wound closure. Furthermore, its treatment regimen led to a high rate of compliance.…”

Section: Discussionmentioning

confidence: 99%

A prospective case series evaluating the safety and efficacy of the Klox BioPhotonic System in venous leg ulcers

Nikolis¹,

Grimard²,

Pesant³

et al. 2016

CWCMR

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Purpose: To investigate the safety and efficacy of the BioPhotonic System developed by Klox Technologies in a case series of ten patients with venous leg ulcers. Patients and methods: Ten patients with chronic venous leg ulcers, having failed on at least one previous therapy, were enrolled into this case series. Results: Nine patients were evaluable for efficacy. A response (defined as decrease in wound surface area) was observed in seven patients (77.8%). Of these, four patients (44.4%) achieved wound closure on average 4 months (127.5 days) following the beginning of the treatment. Two patients did not respond to the investigational treatment. Quality of life improved over time throughout the study. Compliance was excellent, with 93.2% of visits completed as per protocol. Safety was unremarkable, with only four treatment-emergent-related adverse events, for which no specific intervention was required. Conclusion: The BioPhotonic System was shown to be safe and extremely well tolerated. It also demonstrated potential in terms of wound closure, wound surface area decrease, and wound bed preparation.

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Section: Discussionmentioning

confidence: 99%

A prospective case series evaluating the safety and efficacy of the Klox BioPhotonic System in venous leg ulcers

Nikolis¹,

Grimard²,

Pesant³

et al. 2016

CWCMR

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“…There are several studies of wound assessment and treatment such as compression therapy (Escaleira, Cardoso, Rego, Macedo, & Midoes, 2010), how to treat infected wounds (O'Meara, Al-Kurdi, Ologun, & Ovington, 2010), different dressings and wound healing (Lazareth et al, 2007), and the relation between pain and wound healing (Woo & Sibbald, 2009). The complexity of the wound treatment is noticed and so is the importance of a prophylactic consent.…”

Section: Introductionmentioning

confidence: 99%

Feeling confident in burdensome yet enriching care: Community nurses describe the care of patients with hard-to-heal wounds

Eskilsson

Carlsson

2010

International Journal of Qualitative Studies on Health and Well

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Treating patients with hard-to-heal wounds is a complex task that requires a holistic view. Therefore this study focuses on the nurse's perspective with the aim on describing how community nurses experience the phenomenon the care of patients with hard-to-heal wounds. The method used was a reflective lifeworld approach. Seven qualitative interviews with community nurses were conducted. The findings show a tension between enriching and burdensome care. In this tension, the nurses try to find energy to reach harmony in their work through reflection, acceptance, and distance. This is further described by the constituents: “taking responsibility,” “showing respect for the whole person,” “being confident in order to offer confidence,” “seeing time and place as important.” The discussion highlights the importance for a nurse to find how to give ideal care in one's duty but not beyond it. As a consequence the concept “compliance” needs to be challenged in order to promote confidence and mutual trust between nurses and patients. Confidence can be seen as a key, both for nurses and patients, and is dependent on good inter-professional cooperation, competence, and closure.

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“…This result is in line with the observational study by Escaleira et al [38] who included ulcers varying in size from large to small and of durations from short to long and found that this accounted for a significant variance in HTs in the study. However, this study by Escaleira et al [37] is different from the reviewed studies because the medical dressings were applied before the bandage compression, which can contribute to positive HT findings. Small ulcers with short durations are more likely to heal, and their inclusion in the studies can shorten HT [38].…”

Section: Discussionmentioning

confidence: 86%

Challenging the Use of Bandage Compression as the Baseline for Evaluating the Healing Outcomes of Venous Leg Ulcer-Related Compression Therapies in the Community and Outpatient Setting: An Integrative Review

Asaf¹,

Salim²,

Tuffaha³

2018

Dubai Med J

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Background: Venous ulcers have considerable human and financial costs. Bandage compression is the most common type of compression used to enhance healing. Ulcer size, pretreatment ulcer duration, and the consistency of pressure (depending on the competency of the bandager) significantly affect the healing process. Summary: The aim of this review is to explore whether the variability in bandage-related baselines contributes to the differences in healing outcomes among the empirical studies designed to evaluate bandage compression for treating venous ulcers in community and outpatient settings. Two health-related databases were searched: Medline and the Cumulative Index for Nursing and Allied Health. A manual search of relevant reviews and publication reference lists was also undertaken. Fourteen studies were included. The most common study design was a randomized controlled trial. Only one study used a cohort design. This review focused on two variables: healing rate and healing time. The ulcer features, the consistency of the pressure level, and the competency of the bandager were the main factors within the reviewed studies that affect the baselines and healing outcomes. Key Messages: This integrative review confirms that the large variability in the baselines results from differences in the ulcer size, duration, competency level, and amount of pressure that led to differing healing outcomes. Future research designs need to pay attention to make the baselines consistent by ensuring that the ulcer size, duration, competency of the nurses, and level of compression are comparable and consistent within the studies’ design.

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Efficacy of a two-component compression system for the therapy of venous leg ulcers

Abstract: None.

Cited by 13 publications

References 12 publications

A prospective case series evaluating the safety and efficacy of the Klox BioPhotonic System in venous leg ulcers

A prospective case series evaluating the safety and efficacy of the Klox BioPhotonic System in venous leg ulcers

Feeling confident in burdensome yet enriching care: Community nurses describe the care of patients with hard-to-heal wounds

Challenging the Use of Bandage Compression as the Baseline for Evaluating the Healing Outcomes of Venous Leg Ulcer-Related Compression Therapies in the Community and Outpatient Setting: An Integrative Review

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