Efficacy of a kaolin-impregnated gauze in the prevention of postoperative bleeding after cervical conization

Abstract

To evaluate the efficacy of a kaolin-impregnated gauze in preventing postoperative bleeding after a loop electrosurgical excision procedure (LEEP). Methods: The medical records of 1322 women who underwent a LEEP at a university hospital were retrospectively reviewed, of which 1006 patients who fulfilled the inclusion criteria were included in the final analysis. During the study period, the bleeding in patients undergoing a LEEP was managed with the application of a kaolin-impregnated gauze (treatment group, n = 539) or without application of a kaolin-impregnated gauze (control group, n = 467). The primary outcome measure was the incidence of postoperative bleeding requiring hemostatic intervention after a LEEP. A logistic regression model was used to identify the clinical variables for postoperative bleeding. Results: The baseline characteristics were similar between the two study groups. Postoperative vaginal bleeding necessitating an intervention was observed in 12.8% of the study population (129 of 1006 women), with a significant difference between the two groups (9.3% in the treatment group vs. 16.9% in the control group; p < 0.001). On multivariate analysis, significantly lower postoperative bleeding was observed with the use of a kaolinimpregnated gauze than without its use (odds ratio = 0.496; 95% confidence interval = 0.267-0.870; p = 0.009). Conclusions: Prophylactic use of a kaolin-impregnated gauze reduced the incidence of postoperative bleeding after a LEEP.

Safety and efficiency of femoral artery access closure using QuikClot Combat Gauze in patients with severe arterial calcification of access sites

“…Kim et al study (20) presented that the use of HG during preperitoneal pelvic packing (PPP) did not reduce hemorrhage-induced mortality, but did reduce the need for additional packed red blood cell (RBC) transfusions in patients with hemodynamic instability due to severe pelvic fractures. Song et al (21) study revealed that prophylactic use of a kaolin-impregnated gauze reduced the incidence of postoperative bleeding after a loop electrosurgical excision procedure (LEEP). Abbott et al (22) study stated that the use of a kaolin-impregnated intraoperative trauma pad seems to be an effective and inexpensive method to reduce intraoperative blood loss and transfusion volume in pediatric spinal deformity surgery.…”