Efficacy of a Complex Homeopathic Medication (Sinfrontal) in Patients with Acute Maxillary Sinusitis: A Prospective, Randomized, Double-Blind, Placebo-Controlled, Multicenter Clinical Trial

Zabolotnyi, Dmitriy I.; Kneis, Kyra C.; Richardson, A.; Rettenberger, Reinhard; Heger, Marianne; Kaszkin-Bettag, Marietta; Heger, Peter W

doi:10.1016/j.explore.2006.12.007

Cited by 32 publications

(18 citation statements)

References 11 publications

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“…Further, single randomized controlled trials on Esbetritox, Mytrol, Cineole, and Bi Yuan Shu showed some initial positive evidence [125]. A prospective randomized controlled trial compared the homeopathic medication Sinfrontal with placebo among 56 cases and controls with radiograph-confirmed acute maxillary sinusitis [126]. Participants were allowed saline inhalations, paracetemol, and over-the-counter medications; however antibiotics or other conventional therapies for sinusitis were not permitted.…”

Section: Acute Bacterial Rhinosinusitis (Abrs)mentioning

confidence: 99%

Canadian clinical practice guidelines for acute and chronic rhinosinusitis

Desrosiers

Evans

Keith

et al. 2011

All Asth Clin Immun

237

349

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This document provides healthcare practitioners with information regarding the management of acute rhinosinusitis (ARS) and chronic rhinosinusitis (CRS) to enable them to better meet the needs of this patient population. These guidelines describe controversies in the management of acute bacterial rhinosinusitis (ABRS) and include recommendations that take into account changes in the bacteriologic landscape. Recent guidelines in ABRS have been released by American and European groups as recently as 2007, but these are either limited in their coverage of the subject of CRS, do not follow an evidence-based strategy, or omit relevant stakeholders in guidelines development, and do not address the particulars of the Canadian healthcare environment.Advances in understanding the pathophysiology of CRS, along with the development of appropriate therapeutic strategies, have improved outcomes for patients with CRS. CRS now affects large numbers of patients globally and primary care practitioners are confronted by this disease on a daily basis. Although initially considered a chronic bacterial infection, CRS is now recognized as having multiple distinct components (eg, infection, inflammation), which have led to changes in therapeutic approaches (eg, increased use of corticosteroids). The role of bacteria in the persistence of chronic infections, and the roles of surgical and medical management are evolving. Although evidence is limited, guidance for managing patients with CRS would help practitioners less experienced in this area offer rational care. It is no longer reasonable to manage CRS as a prolonged version of ARS, but rather, specific therapeutic strategies adapted to pathogenesis must be developed and diffused.Guidelines must take into account all available evidence and incorporate these in an unbiased fashion into management recommendations based on the quality of evidence, therapeutic benefit, and risks incurred. This document is focused on readability rather than completeness, yet covers relevant information, offers summaries of areas where considerable evidence exists, and provides recommendations with an assessment of strength of the evidence base and degree of endorsement by the multidisciplinary expert group preparing the document.These guidelines have been copublished in both Allergy, Asthma & Clinical Immunology and the Journal of Otolaryngology-Head and Neck Surgery.

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Section: Acute Bacterial Rhinosinusitis (Abrs)mentioning

confidence: 99%

Canadian clinical practice guidelines for acute and chronic rhinosinusitis

Desrosiers

Evans

Keith

et al. 2011

All Asth Clin Immun

237

349

View full text Add to dashboard Cite

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“…A prospective, randomized, double-blind, placebo-controlled, multicenter, clinical trial comparing Sinfrontal with placebo in 113 patients with radiography-confirmed acute maxillary sinusitis found that there was a significant difference in patients treated with Sinfrontal with no recurrence of symptoms 8 weeks after treatment. 111 Patients receiving Sinfrontal were instructed to take 1 tablet every hour until improvement was noted, with a maximum of 12 tablets per day, after which the dosing would change to 2 tablets 3 times per day. An economic analysis demonstrated that Sinfrontal can lead to substantial cost savings with markedly reduced absenteeism from work.…”

Section: Sinfrontalmentioning

confidence: 99%

Complementary and Integrative Treatments

Taw¹,

Nguyen

Wang

2013

Otolaryngologic Clinics of North America

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Rhinosinusitis is characterized by inflammation of the mucosa involving the paranasal sinuses and the nasal cavity and is one of the most common health care problems, with significant impairment of quality of life. There is a growing amount of interest in the use of complementary and integrative medicine for the treatment of rhinosinusitis. This article focuses on an integrative approach to rhinosinusitis.

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“…Since some of this initial research, other applications for homeopathy have been analyzed in clinical trials, including postoperative pain, 25 sinusitis, 26 injuries, 27 skin conditions, 28 and ADHD, 29 among many others. The results have been mixed, with some trials showing no effect.…”

Section: Various Complementary and Alternative Medicine Modalitiesmentioning

confidence: 99%

An Overview of CAM

2009

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Complementary and alternative medicine (CAM), more recently known as integrative health or integrative medicine, is a diverse field comprising numerous treatments and practitioners of various levels of training. This review defines several of the main CAM modalities and reviews some of the research relevant to their clinical application. The goal is to provide healthcare providers with a basic understanding of CAM to start the incorporation of proven treatments into their clinical practice as well as guide them to working with CAM providers; ultimately, such knowledge is a fundamental part of a collaborative approach to optimal patient health and wellness.

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Efficacy of a Complex Homeopathic Medication (Sinfrontal) in Patients with Acute Maxillary Sinusitis: A Prospective, Randomized, Double-Blind, Placebo-Controlled, Multicenter Clinical Trial

Cited by 32 publications

References 11 publications

Canadian clinical practice guidelines for acute and chronic rhinosinusitis

Canadian clinical practice guidelines for acute and chronic rhinosinusitis

Complementary and Integrative Treatments

An Overview of CAM

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