Efficacy of 99mTc-sestamibi SPECT/CT for minimally invasive parathyroidectomy: comparative study with 99mTc-sestamibi scintigraphy, SPECT, US and CT

Abstract

We correctly identified the precise location of parathyroid adenomas or hyperplasia by (99m)Tc-sestamibi SPECT/CT which was helpful to perform MIP.

Usefulness of SPECT/CT in Parathyroid Lesion Detection in Patients with Thyroid Parenchymal 99mTc-Sestamibi Retention

“…Compared to other conventional imaging modalities such as ultrasonogram (US), computed tomography (CT), and magnetic resonance (MR), 99m Tc-2-methoxy-2-methylpropyl isonitrile ( 99m Tc-sestamibi, MIBI) parathyroid scintigraphy has been shown to have higher sensitivity in detecting parathyroid adenomas [1,2]. In addition, the anatomical information provided by single positron emission computed tomography/computed tomography (SPECT/ CT) has improved the detection and localization of parathyroid lesions compared to planar scans alone [3,4].…”

A comparison between 11C-methionine PET/CT and MIBI SPECT/CT for localization of parathyroid adenomas/hyperplasia

“…It has also been reported that hybrid imaging, which combines SPECT with computed tomography (SPECT/CT), contributes to surgical planning by adding anatomical information, especially in patients with ectopic adenomas or with previous neck surgery [3]. A higher sensitivity of MIBI SPECT/CT compared with MIBI SPECT or planar scintigraphy has also been reported [4].…”

Brown tumors mimicking bone and lung metastases: Key role of radionuclide imaging

“…The procedure may include a hybrid SPECT/CT acquisition, which is useful in localizing the pathological parathyroid gland and identifying ectopic adenomas [9]. This precise location is helpful to perform minimally invasive parathyroidectomy [15]. Sestamibi uptake within brown tumors and bone metastases has also been described [14,16].…”