Efficacy of 2 types of silicone hydrogel bandage contact lenses after photorefractive keratectomy

Grentzelos, Michael A.; Plainis, Sotiris; Astyrakakis, Nikolaos; Diakonis, Vasilios F.; Kymionis, George D.; Kallinikos, Panagiotis A.; Pallikaris, Ioannis G.

doi:10.1016/j.jcrs.2009.07.015

Cited by 50 publications

(44 citation statements)

References 15 publications

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“…The rate of wound healing is of great importance when considering a bandage contact lens material ensuring a faster healing process and less discomfort for the patient. [ 27 ] Specifi c investigation of the closed cell monolayers was undertaken by staining for zonal occludens-1 (ZO-1). The ZO-1 protein functions in the formation of tight junctions which are expressed around the cell membrane when a cell monolayer is intact and the epithelial barrier functioning.…”

Section: Doi: 101002/adhm201600258mentioning

confidence: 99%

A Novel Peptide Hydrogel for an Antimicrobial Bandage Contact Lens

Gallagher

Alorabi

Wellings

et al. 2016

Adv Healthcare Materials

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A peptide hydrogel with an antimicrobial activity is developed as a bandage contact lens. The antimicrobial activity is enhanced with the addition of the biomolecules penicillin G or poly‐ε‐lysine and is positive against Staphylococcus aureus and Escherichia coli. The lens is also noncytotoxic toward a human corneal epithelial cell line and as a consequence is of great potential as a drug‐eluting bandage lens replacing conventional corneal ulcer treatment.

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Section: Doi: 101002/adhm201600258mentioning

confidence: 99%

A Novel Peptide Hydrogel for an Antimicrobial Bandage Contact Lens

Gallagher

Alorabi

Wellings

et al. 2016

Adv Healthcare Materials

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“…Eyes bandaged with higher transmissibility lenses also achieved significantly better visual acuity and had reduced haze for up to a month [130]. Combining these outcomes with those from studies using lens pairs of more modest differential transmissibility [131][132][133], suggests that similar benefits might accrue down to at least 110 barrers/cm; although inconsistent specification of Dk/t among some of these reports does introduce additional uncertainty.…”

Section: Bandage Lensesmentioning

confidence: 99%

The significance of oxygen during contact lens wear

Papas

2014

Contact Lens and Anterior Eye

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“…9 They found no statistically significant difference in terms of re-epithelisation degree and pain levels. Engle et al reported that corneal re-epithelialization after PRK was faster with less subjective complaints within the first 48 hours with lotrafilcon-A BCL compared to those with hydrogel BCL.…”

Section: 910mentioning

confidence: 89%

“…9 The aim of using BCL is to increase patient comfort by reducing pain induced by ocular irritation. Gıl-Casorla et al study was unable to determine a statistically significant difference concerning patient answers to questions intended at determining subjective complaints.…”

Section: 910mentioning

confidence: 99%

Comparison of Two Different Bandage Contact Lens Types Used After Corneal Crosslinking

Halili¹,

Acar²,

Yenerel³

2015

Turkiye Klinikleri J Ophthalmol

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A AB BS S T TR RA AC CT T O Ob bj je ec ct ti iv ve e: : To compare the efficiacy of two types of silicone hydrogel bandage contact lenses (BCLs) after corneal collagen crosslinking (CXL) in keratoconus patients. M Ma at te er ri ia al l a an nd d M Me et th ho od ds s: : In this prospective study, 36 keratoconus patients received CXL in both eye. Each patient received a BCL composed of balafilcon A (Pure Vision; Bauch&Lomb) (14.0 diameter, 8.6 base curve) in 1 eye and lotrafilcon B (Air Optix Aqua; Ciba Vision) (14.2 diameter, 8.6 base curve) in the fellow eye. Patients were masked to the lens type in each eye. Postoperative medication regimen was the same with both eye. Epithelial defect size, contact lens debris, conjunctival and limbal hyperemia, reepithelization and responses to a subjective-comfort questionnaire were assessed postoperatively at 1, 3, and 5 days. A paired Student's t test and chi-square tests were used when appropriate. R Re es su ul lt ts s: : Seventy-two eyes of 36 keratoconus patients who underwent CXL were analyzed. There was no statistically significant difference in epithelial defect size, conjunctival or limbal hyperemia between the 2 lenses at any postoperative visit. Three days postoperatively, re-epithelization was complete in 77.8% of eyes (28 eyes) in the balafilcon A group and 83.3% of the eyes (30 eyes) in the lotrafilcon B group. Lens deposition and patient discomfort was significantly higher with the balafilcon A group 5 days postoperatively (p<0.01 for both comparisons). C Co on nc cl lu us si io on n: : There were no differences in corneal re-epithelization between the 2 types of BCLs (p>0.01). However, lens deposition and patient discomfort was higher with balafilcon A (p<0.01).K Ke ey y W Wo or rd ds s: : Contact lenses; keratoconus; riboflavin Ö ÖZ ZE ET T A Am ma aç ç: : Keratokonus hastalarında kornea kollajen kroslink (KKK) sonrası kullanılan iki farklı tip bandaj kontakt lensin etkinliğinin karşılaştırılması. G Ge er re eç ç v ve e Y Yö ön nt te em ml le er r: : Bu prospektif çalışma ile KKK uygulanan 36 keratokonus hastası değerlendirildi. Hastaların bir gözüne balafilcon A içe-rikli bandaj kontakt lens (BKL) (Pure Vision; Bauch&Lomb) (14,0 çap, 8,6 temel eğri), diğer gözle-rine lotrafilcon B içerikli BKL (Air Optix Aqua; Ciba Vision) (14,2 çap, 8,6 temel eğri) önerildi. Hastaların her bir gözüne bu lens tiplerinden biri uygulandı. Ameliyat sonrası her iki göz için aynı medikal tedavi rejimleri uygulandı. Ameliyat sonrası 1.,3.,ve 5. günlerde epitel defektinin büyük-lüğü, kontakt lens debris, konjonktival ve limbal hiperemi, tekrar epitelizasyon ve subjektif konfor anketine cevaplar değerlendirildi. Sonuçların değerlendirilmesinde eşleştirilmiş Student t test ve ki-kare testi kullanıldı. B Bu ul lg gu ul la ar r: : KKK olan 36 keratokonus hastasının 72 gözü değerlendirildi. Ameliyat sonrası epitel defekt büyüklüğü, konjonktival ve limbal hiperemi açısından değerlendirildi-ğinde her iki kontakt lens arasında istatistiksel olarak anlamlı fark saptanmadı. Ameliyat son...

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Efficacy of 2 types of silicone hydrogel bandage contact lenses after photorefractive keratectomy

Abstract: There were no differences in corneal reepithelialization or subjective measurements after PRK between the 2 types of silicone hydrogel bandage contact lenses.

Cited by 50 publications

References 15 publications

A Novel Peptide Hydrogel for an Antimicrobial Bandage Contact Lens

A Novel Peptide Hydrogel for an Antimicrobial Bandage Contact Lens

The significance of oxygen during contact lens wear

Comparison of Two Different Bandage Contact Lens Types Used After Corneal Crosslinking

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