Efficacy in reducing dentine hypersensitivity of a regimen using a toothpaste containing 8% arginine and calcium carbonate, a mouthwash containing 0.8% arginine, pyrophosphate and PVM/MA copolymer and a toothbrush compared to potassium and negative control regimens: An eight-week randomized clinical trial

Abstract

Arginine regimen provided the greatest reduction in Tactile and Air-Blast dentine hypersensitivity compared to potassium and negative control regimens; and provides faster dentine hypersensitivity relief than potassium regimen.

Management of dentine hypersensitivity: efficacy of professionally and self‐administered agents

“…Two studies used a potassium positive control (Elías Boneta et al. ,b) and one also incorporated a conventional fluoride negative control mouthrinse (Elías Boneta et al. ), and a third used only a conventional fluoride negative control (Hu et al.…”

“…The PVA/MA product formulations were combined with arginine (3) (Elías Boneta et al. ,b, Hu et al. ), Triclosan (1) (Chaknis et al.…”

“…The majority of studies involved the application of self‐administered potassium products; toothpastes (21), mouthrinses (2) (Elías Boneta et al. ,b) and the remainder (2) evaluated professionally applied products (Craig et al. , Talesara et al.…”

“…), and two combining mouthrinse and toothpaste in the design (Elías Boneta et al. ,b). Of the seven studies, three had a negative control product included in the design as well.…”

New toothpaste to deal with dentine hypersensitivity: double‐blind randomized controlled clinical trial

“…Clinical trials, as well as in vitro and in situ research of the toothpaste compounds, have resulted in much controversy on the efficacy of potassium ingredients contained in the oral products and, although not implying to them as ineffective, consider them rather inferior in comparison with other toothpaste technologies, as implying for instance to just recently studied arginine‐based products .…”