Efficacy and Toxicity of Calcitonin Treatment in Children with Cherubism: A Single-Center Cohort Study
Willem H. Schreuder,
Ethan B. Meijer,
Arjen H.G. Cleven
et al.
Abstract:Cherubism is a rare autosomal dominant disease characterized by expansile osteolytic jawbone lesions. The effect and safety of off‐label calcitonin treatment during the progressive phase of the disease are not well described. In this retrospective study, we present data on the radiological response and adverse effects of subcutaneously administered calcitonin in a cohort of nine cherubism children (3 female, 6 male). Two of the nine patients underwent two separate treatment courses with a significant off‐treat… Show more
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