Myocardial ischemia (MI) is a condition with deficient oxygen and nutrients supply, which is characterized by ischemic necrosis of heart muscle (Gao et al., 2019a;Kloner & Rezkalla, 2004). MI-induced infarction is one of main reasons for affecting human death globally. MI is often accompanied by biochemical changes, such as oxidative stress (Han et al., 2009). It has been reported that there are various anti-myocardial ischemic drugs and adjuvants that can effectively reduce cardiovascular events, while the potentially serious adverse effects remain a key challenge (Liu & Huang, 2016).In recent years, it has been achieved great advancement that traditional Chinese medicine (TCM) could prevent and treat cardiovascular and cerebrovascular diseases (