Efficacy and safety of TachoSil® versus standard treatment of air leakage after pulmonary lobectomy☆☆☆

Abstract

TachoSil® was superior to standard surgical treatment in reducing both postoperative air leakage duration and intra-operative air leakage intensity in patients undergoing elective pulmonary lobectomy.

Management of unexpected intraoperative bleeding during thoracoscopic pulmonary resection: a single institutional experience

“…Its efficacy and safety for preventing air leaks after lobectomy have been reported [20,21], and while it has resulted in decreased postoperative air leakage, there are few reports [22] on the use of TachoSil for unexpected intraoperative bleeding. In the present study, this kind of bleeding was successfully controlled with TachoSil under VATS in three (75 %) of four cases.…”

Editorial commentUse of sealants in pulmonary surgery: evidence-based or industry-driven approach?

“…The article from Marta and colleagues [2] is the largest RCT ever published on collagen fleece-bound sealant.…”

“…What we already know: evidence from the literature Including the trial published in this issue [2], there have been five randomised trials testing the efficacy of collagen fleece-bound sealants in pulmonary resection [3].…”

Use of local pro-coagulant haemostatic agents for intra-cavity control of haemorrhage after trauma

“…TachoSil has been shown to be an effective sealing or haemostatic agent in randomised controlled trials for various surgical procedures including lung, hepatic, renal and cardiovascular surgery [17][18][19][20][21]. The successful use of TachoSil has also been described in a wide range of other surgical settings [22].…”