Efficacy and Safety of Micropulse Transscleral Laser Therapy in Silicone Oil-induced Glaucoma

Zbiba, W.; Sayadi, Sana; Kharrat, Malek; Daoued, Maroua

doi:10.1097/ijg.0000000000002051

Cited by 4 publications

(9 citation statements)

References 33 publications

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“…Similarly to the findings of Zbiba [ 17 ], the subgroup analysis of silicone oil induced IOP elevations showed decrease of more than 43%, even though silicone oil removal was not performed prior to or during the procedure. No underlying correlation was uncovered that can be added to the current existing hypothesis that the absence of vitreous gel promotes the posterior movement of the ciliary body during the laser procedure [ 17 ].…”

Section: Discussionsupporting

confidence: 75%

The effect of cumulative energy in repeated subliminal transscleral cyclophotocoagulation: a retrospective study

Szabó,

Árpádffy-Lovas,

Hagyó

et al. 2024

BMC Ophthalmol

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Background The long-term safety and efficacy of repeated applications of subliminal transscleral cyclophotocoagulation (SL-TSCPC) with a focus on cumulative energy was evaluated in glaucoma patients. Methods In this retrospective, multicentric study the data of a total of 82 eyes with various causes of glaucoma that were treated with a single or multiple applications of SL-TSCPC were collected. Treatments were performed under general or local anesthesia with an 810 nm diode laser. Power was 2000 mW; duty cycle, 31.3%; total treatment duration, 80–320 s; equaling a total energy of 50–200 J per treatment session. Fifty-five eyes (55 patients) presented for all follow-ups, and these eyes were selected for further statistical analysis. The mean age was 60.0 ± 17.1 years, and 22 (40%) of the patients were female. Intraocular pressure (IOP) and dependence on further glaucoma medication were evaluated at 12 months following the initial treatment. Results Eyes underwent 1 or 2 consecutive SL-TSCPC treatments. Median (min–max) baseline IOP of 34 (13–69) decreased to 21.5 (7–61), 22 (8–68), 20 (9–68), and 19.5 (3–60) mmHg at the 1, 3, 6, and 12-month postoperative timepoints respectively. The mean (± SD) IOP decrease at 12 months was 26 ± 27%, 39 ± 32%, and 49 ± 33% in the low (below 120 J, n = 18), medium (120–200 J, n = 24), and high (above 200 J, n = 13) cumulative energy groups respectively. At the 12-month timepoint, oral carbonic anhydrase use was discontinued in ¾ of the cases. Conclusions It was found that the repeated application of SL-TSCPC safely and efficiently decreases IOP in a Caucasian population with heterogenous causes of glaucoma, eyes with silicone oil responded to a greater extent. Inclusion of cumulative energy scales may contribute to better addressing repeated procedures in a standardized fashion.

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Section: Discussionsupporting

confidence: 75%

The effect of cumulative energy in repeated subliminal transscleral cyclophotocoagulation: a retrospective study

Szabó,

Árpádffy-Lovas,

Hagyó

et al. 2024

BMC Ophthalmol

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“…The literature data on secondary glaucoma developed after the vitreoretinal procedure. Table A1 provides details of MP-CPC studies on secondary glaucoma previously published in the literature [ 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 ]. The literature data are difficult to compare because the definition of success varies from study to study, the etiology is diverse, and therefore the success rates calculated at the end of follow-up period show a wide variation (from 11.0% to 95.7%; for details see Table A1 ).…”

Section: Discussionmentioning

confidence: 99%

“…We selected for inclusion in the discussion those publications in which we found references to MP-CPC for the treatment of secondary glaucoma, especially which developed after vitreoretinal procedure. Regarding the prospective studies, except for the study of Zbiba et al, 2022 [ 10 ], the others (Tan et al, 2010 [ 35 ], Aquino et al, 2015 [ 34 ], Barac et al, 2018 [ 26 ], and Jammal et al, 2019 [ 19 ]) were not addressed to analyze silicon oil-induced glaucoma as a different subgroup. In these studies, the success rates ranged from 52–72%; in one study the success rate was not applicable.…”

Section: Discussionmentioning

confidence: 99%

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Micropulse Transscleral Cyclophotocoagulation Results in Secondary Glaucoma

Szilagyi

Kránitz

Nagy

et al. 2023

Life

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The aim of this study was to analyze the long-term outcome of first session of micropulse transscleral cyclophotocoagulation (MP-CPC) for refractory glaucoma developed after vitreoretinal surgery combined with silicone oil implantation. The inclusion criteria of this consecutive case series were: patients with secondary glaucoma in the refractory stage who underwent MP-CPC between 2018 and 2021, vitreoretinal surgery combined with silicon oil implantation, and at least a 24-month follow-up period after MP-CPC. Success was defined as the baseline eye pressure reduced at least 20%, and it should be ranged between 10 to 20 mmHg without further MP-CPC at the end of the follow-up. For this retrospective study, 11 eyes of 11 patients were selected. The reduction in IOP was found to be significant (p = 0.004) at the end of the follow-up time, and the success rate was 72% according to our results. The change in the number of antiglaucoma agents in the administered eyedrops was not significant compared to the baseline values. At the end of the follow-up period the change in BCVA values was not significant (p = 0.655). Our results confirm significant IOP lowering effect of this subthreshold method preserving visual performance safely even in eyes with previous vitrectomy surgery with a silicone oil implantation.

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“…The laser uses micropulse instead of continuous wave energy to reduce side effects caused by thermal energy. The technique has gained popularity as a non-invasive mode of glaucoma therapy especially during the COVID-19 pandemic with no major side effects being reported unlike continuous wave diode laser cyclophotocoagulation 1–3…”

Section: Descriptionmentioning

confidence: 99%

Conjunctival laceration and burn with micropulse transscleral laser therapy (MP-TLT)

Bukke,

Wahi,

Angku

et al. 2023

BMJ Case Rep

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Efficacy and Safety of Micropulse Transscleral Laser Therapy in Silicone Oil-induced Glaucoma

Abstract: The purpose of this study was to assess the efficiency and safety of micropulse transscleral laser therapy (MP-TLT) in the management of silicone oil-induced glaucoma (SOG).

Cited by 4 publications

References 33 publications

The effect of cumulative energy in repeated subliminal transscleral cyclophotocoagulation: a retrospective study

The effect of cumulative energy in repeated subliminal transscleral cyclophotocoagulation: a retrospective study

Micropulse Transscleral Cyclophotocoagulation Results in Secondary Glaucoma

Conjunctival laceration and burn with micropulse transscleral laser therapy (MP-TLT)

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