Efficacy and safety of lornoxicam vs ibuprofen in primary dysmenorrhea: a randomized, double-blind, double dummy, active-controlled, cross over study

Patel, Jayshree C.; Patel, Pooja; Acharya, Hemangini; Nakum, Kanaklata; Tripathi, Chandra Bhushan

doi:10.1016/j.ejogrb.2015.03.005

Cited by 9 publications

(7 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Vsi analizirani članki (Daniels, et al, 2009;Zahradnik, et al, 2010;Ghodsi & Asltoghiri, 2014;Patel, et al, 2015;Al-Jefout & Nawaiseh, 2016) opisujejo pozitivne učinke farmakološkega zdravljenja primarne dismenoreje. Daniels in sodelavci (2009), Zahradnik in sodelavci (2010), Patel in sodelavci (2015) ter Al-Jefout in Nawaiseh (2016) so v svojih raziskavah proučevali učinkovitost zdravljenja primarne dismenoreje z nesteroidnimi protivnetnimi zdravili (NSAID).…”

Section: Diskusijaunclassified

“…Daniels in sodelavci (2009), Zahradnik in sodelavci (2010), Patel in sodelavci (2015) ter Al-Jefout in Nawaiseh (2016) so v svojih raziskavah proučevali učinkovitost zdravljenja primarne dismenoreje z nesteroidnimi protivnetnimi zdravili (NSAID). Ker ponujajo precejšnje zmanjšanje bolečine pri večini žensk, avtorji izvedenih raziskav (Zahradnik, et al, 2010;Patel, et al, 2015) podpirajo njihovo uporabo kot prvo izbiro za lajšanje bolečih menstruacij. Dolžina zdravljenja, ki dosega izboljšanje simptomov primarne dismenoreje, je pri nesteroidnih protivnetnih zdravilih krajša kot pri hormonskem zdravljenju (Zahradnik, et al, 2010).…”

Section: Diskusijaunclassified

“…Oralna kontracepcijska sredstva so običajno zdravilo druge izbire pri zdravljenju simptomov primarne dismenoreje (Daniels, et al, 2009). Avtorji nekaterih raziskav (Daniels, et al, 2009;Zahradnik, et al, 2010;Patel, et al, 2015) svetujejo jemanje peroralne kontracepcije ženskam, ki se ne odzivajo na zdravljenje z nesteroidnimi protivnetnimi zdravili ali so zanje kontraindicirane, saj so ugotovili, da učinkovito zmanjša simptome boleče menstruacije.…”

Section: Diskusijaunclassified

“…Smernice (Antao, 2005) priporočajo terapijo s toploto, ki se lahko kombinira s farmakološko obliko (tabletami Ibuprofen). Avtorji / Authors Kategorija 1: farmakološko zdravljenje primarne dismenoreje oralna kontracepcija -nesteroidna protivnetna zdravilaplacebo zdravilo -kapsule -terapevtsko zdravilo -učinkovitost zdravil -zdravilo prve izbire -zdravilo druge izbire Daniels, et al, 2009;Zahradnik, et al, 2010;Ghodsi & Asltoghiri, 2014;Patel, et al, 2015;Al-Jefout & Nawaiseh, 2016 Kategorija 2: nefarmakološko zdravljenje primarne dismenoreje fizioterapija -terapija s toploto -TENS-terapija -joga -Keglove vaje -tek -vaje sproščanja -splošno raztezanjekapsule ingverja -kapsule cinkovega sulfata -tradicionalna kitajska medicina -akupunktura -akupresura -aromaterapija Kannan & Claydon, 2014;Kashefi, et al, 2014;Abaraogu & Tabanasi-Ochuogu, 2015;Ortiz, et al, 2015;Lee, et al, 2016;Igwea, et al, 2016;Abaraogu, et al, 2016;Sut & Kahyaoglu-Sut, 2017 Legenda / Legend: TENS -transkutana električna stimulacija živcev / transcutaneous electrical nerve stimulation Kashefi in sodelavci (2013) so ugotovili, da kapsule ingverja in cinkovega sulfata učinkovito zmanjšujejo bolečino pri primarni disminoreji. Tudi Daily in sodelavci (2015) navajajo, da so šumeče ingverjeve tablete pomagale zmanjšati bolečino, ki so jo ocenili z vizualno analogno lestvico bolečine.…”

Section: Diskusijaunclassified

See 3 more Smart Citations

Farmakološka in nefarmakološka terapija za zdravljenje primarne dismenoreje

Kavšak¹,

Avdylaj²

2018

Obzor Zdrav Neg

View full text Add to dashboard Cite

Uvod: V prispevku smo na podlagi sistematičnega pregleda literature identificirali različne oblike farmakološkega in nefarmakološkega zdravljenja, ki lahko ženskam s primarno dismenorejo pomagajo zmanjšati intenziteto bolečine. Namen raziskave je bil namreč ugotoviti oblike farmakološke in nefarmakološke terapije za zmanjšanje bolečine pri primarni dismenoreji.Metode: Za iskanje literature so bile uporabljene podatkovne baze: CINAHL, Medline, ScienceDirect in Cochrane Library. Uporabljeni so bili naslednji iskalni pojmi: primarna dismenoreja, menstrualna bolečina, farmakološko zdravljenje, nefarmakološko zdravljenje; v angleškem jeziku: primary dysmenorrhea, menstrual pain, pharmalogical intervention, non-pharmacological intervention. Iskanje je bilo omejeno na znanstvene revije, recenzirane publikacije, dostopne v celotnem besedilu, besedila, objavljena v angleškem jeziku v obdobju 2007–2017. Skupaj je bilo identificiranih 571 zadetkov, v končno analizo je bilo vključenih 13 raziskav, ki so ustrezale namenu raziskave.Rezultati: Analiziranih je bilo 13 raziskav, od tega pet farmakoloških in osem nefarmakoloških oblik zdravljenja. Rezultati raziskave so pokazali, da nesteroidna protivnetna zdravila ponujajo precejšnje zmanjšanje bolečine pri večini žensk s primarno dismenorejo. Ugotovitve kažejo, da vse oblike nefarmakološkega zdravljenja niso priporočljive in pri pacientkah s primarno dismenorejo ne pomagajo zmanjšati intenzitete bolečine. Diskusija in zaključek: Rezultati sistematičnega pregleda literature kažejo, da farmakološko zdravljenje učinkoviteje zmanjšuje intenziteto bolečine, saj se učinek delovanja zdravila izkaže v eni uri po zaužitju, vendar povzroča nekatere stranske učinke.

show abstract

Section: Diskusijaunclassified

See 2 more Smart Citations

Farmakološka in nefarmakološka terapija za zdravljenje primarne dismenoreje

Kavšak¹,

Avdylaj²

2018

Obzor Zdrav Neg

View full text Add to dashboard Cite

show abstract

“…1 Although primary dysmenorrhea is associated with abnormal myometrial contractions due to abnormal elevation in the levels of prostaglandins, reduction in uterine blood flow, and generalized ischemia due to vasoconstriction, the underlying cause of pain in primary dysmenorrhea has not yet been clarified. 2 During the menstrual cycle, there is a decrease in the uterine artery pulsatility index (PI) values parallel to blood flow in the uterine artery during the luteal phase to ensure compliance with implantation. However, it is observed that the uterine artery PI values are high during the menstrual cycle.…”

Section: Introductionmentioning

confidence: 99%

The Relationship between Serum Ischemia-Modified Albumin Levels and Uterine Artery Doppler Parameters in Patients with Primary Dysmenorrhea

Sen

Özdemir

et al. 2020

Rev Bras Ginecol Obstet

View full text Add to dashboard Cite

Objective Primary dysmenorrhea occurs due to abnormal levels of prostanoids, uterine contractions, and uterine blood flow. However, the reasons for pain in primary dysmenorrhea have not yet been clarified. We examined the blood flow alterations in patients with primary dysmenorrhea and determined the relationship between ischemia-modified albumin (IMA) levels, as an ischemia indicator, and primary dysmenorrhea. Methods In the present study, 37 patients who had primary dysmenorrhea and were in their luteal and menstrual phase of their menstrual cycles were included. Thirty individuals who had similar demographic characteristics, who were between 18 and 30 years old and did not have gynecologic disease were included as control individuals. Their uterine artery Doppler indices and serum IMA levels were measured. Results Menstrual phase plasma IMA levels were significantly higher than luteal phase IMA levels, both in the patient and in the control groups (p < 0.001). Although the menstrual phase IMA levels of patients were significantly higher than those of controls, luteal phase IMA levels were not significantly different between the two groups. Menstrual uterine artery pulsatility index (PI) and resistance index (RI) of primary dysmenorrhea patients were significantly different when compared with luteal uterine artery PI and RI levels. There was a positive correlation between menstrual phase IMA and uterine artery PI and RI in the primary dysmenorrhea. Conclusion Ischemia plays an important role in the etiology of the pain, which is frequently observed in patients with primary dysmenorrhea. Ischemia-modified albumin levels are considered as an efficient marker to determine the severity of pain and to indicate ischemia in primary dysmenorrhea.

show abstract

Therapeutic effects of traditional Chinese herbal prescriptions for primary dysmenorrhea

Dorjbat

Si-chao

et al. 2019

Chinese Herbal Medicines

View full text Add to dashboard Cite

Efficacy and safety of lornoxicam vs ibuprofen in primary dysmenorrhea: a randomized, double-blind, double dummy, active-controlled, cross over study

Cited by 9 publications

References 22 publications

Farmakološka in nefarmakološka terapija za zdravljenje primarne dismenoreje

Farmakološka in nefarmakološka terapija za zdravljenje primarne dismenoreje

The Relationship between Serum Ischemia-Modified Albumin Levels and Uterine Artery Doppler Parameters in Patients with Primary Dysmenorrhea

Therapeutic effects of traditional Chinese herbal prescriptions for primary dysmenorrhea

Contact Info

Product

Resources

About