Efficacy and Safety of Intranasal Dexmedetomidine versus Oral Chloral Hydrate as Sedatives for Pediatric Patients: A Systematic Review and Meta-Analysis
Abstract:This study was designed to review published literature to determine the efficacy and safety of intranasal dexmedetomidine versus oral chloral hydrate (CH) for sedation in pediatric patients based on qualified studies. We searched the PubMed, Cochrane, and Embase databases for qualified studies published before March 2021. For each study, we analyzed the relative risk or weighted mean difference combined with a 95% CI. Fourteen studies including 3749 pediatric patients were included in this meta-analysis. Compa… Show more
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