Efficacy and safety of inhalation budesonide in the treatment of pediatric asthma in the emergency department: a systematic review and meta-analysis

Viswanatha, Gollapalle Lakshminarayanashastry; Shylaja, H.; Nandakumar, Krishnadas; Venkataranganna, Marikunte V; Prasad, N. B. L.

doi:10.1007/s43440-020-00098-y

Cited by 3 publications

(1 citation statement)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[10,11]. BUD, also treat the inflammation, and during times of deteriorating manifestations, there is indication of a "window of opportunity" in which prompt ICS administration may avoid the signs from escalating into an exacerbation [12].…”

Section: Introductionmentioning

confidence: 99%

Effect of Budesonide Inhalation on Asthmatic Child: A Randomized Controlled Trial

Saad

Moursi²

2023

JAMMR

View full text Add to dashboard Cite

Background: Asthma is a diverse inflammatory airway illness characterized by intermittent respiratory manifestations, and inhaled steroids (ICS) constitute the foundation of all asthma management regimens. The aim of this study was to examine the therapeutic efficacy of inhaled Budesonide (BUD) regimens for recurrent wheeze treatment in pre-schoolers. Methods: This retrospective randomized controlled research involved 70 pediatric subjects aged from 6-12 years old, both sexes having four wheezing episodes or more in the last year; and satisfying at least one main condition or two minor of them. Case selection was rigorously regulated by experts who specialize in children’s respiratory disorders diagnosis and treatment, notably asthma. The included children had mild-to-moderate asthma. Results: After treatment, FEV1, FVC and FEV1: FVC were significantly elevated in group A than group B (P value <0.001). Urgent care visits and hospitalizations because of asthma were significantly lower in group A than group B (P value = 0.003 and 0.008 respectively). Conclusions: We have shown that the BUD Inhalation is an effective and safe management for long term asthma treatment. Compared to placebo, BUD was related with a higher decrease in asthma manifestations and a rise in the number episode free days.

show abstract

Section: Introductionmentioning

confidence: 99%