Efficacy and Safety of Immediate Angioplasty Versus Ischemia-Guided Management After Thrombolysis in Acute Myocardial Infarction in Areas With Very Long Transfer Distances

Bøhmer, Ellen; Hoffmann, Pavel; Abdelnoor, Michael; Arnesen, Harald; Halvorsen, Sigrun

doi:10.1016/j.jacc.2009.08.007

Cited by 228 publications

(158 citation statements)

References 29 publications

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“…It was argued back in the 1990s that primary PCI offered the best treatment results [28]. At that time, patients successfully treated with thrombolytic therapy did not regularly undergo CAG [29].…”

Section: Discussionmentioning

confidence: 99%

Treatment of acute myocardial infarction in the sub-arctic region of Norway. Do we offer an equal quality of care?

Norum

Hovland

Balteskard

et al. 2017

International Journal of Circumpolar Health

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Patients, relatives, healthcare workers and administrators are concerned about the quality of care offered. We aimed to explore the treatment of acute myocatrdial infarction (AMI) in Northern Norway, compare it with the national figures, and document whether there is an equal quality of care or not. The retrospective study included data on patients' treatment for AMI. The following sources were employed. The Norwegian Patient Registry, National Quality of Care Database, Norwegian Myocardial Infarction Registry and data from the National Air Ambulance Services of Norway. The period 2012-2014/15 was studied and the variables were: incidence of AMI, gender and age adjusted rates of AMI and revascularization (PCI, CABG) based on patient's place of living (according to hospital catchment area) and 30-day survival rate. The annual incidence of AMI was 9% higher in the northern region. Significant incidence variations (2.7–5.9 AMI/1000 inhabitants) between the hospitals' catchment areas were revealed. The 30-day survival rate varied between 85.1–92.1% between hospitals. The variation in revascularization/AMI rate was 0.72–1.54. Air amublance services' availability varied through the day. In conclusion, significant variations in the AMI rate and an unequal service within the region was revealed.

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Section: Discussionmentioning

confidence: 99%

Treatment of acute myocardial infarction in the sub-arctic region of Norway. Do we offer an equal quality of care?

Norum

Hovland

Balteskard

et al. 2017

International Journal of Circumpolar Health

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“…We have used the (19) GRACIA I (Routine invasive strategy within 24 hours of thrombolysis versus ischemia-guided conservative approach for acute myocardial infarction with ST-segment elevation), (20) CARESS-in-AMI (Combined Abciximab REteplase Stent Study in Acute Myocardial Infarction), (21) TRANSFER-AMI (Trial of Routine Angioplasty and Stenting after Fibrinolysis to Enhance Reperfusion in Acute Myocardial Infarction), (22) and NORDISTEMI (Norwegian study on District treatment of STElevation Myocardial Infarction) (23) as summarized in Table 1. In order to maintain clinical homogeneity in our meta-analysis, we excluded other trials such as PRAGUE (Primary Angioplasty in patients transferred from General community hospitals to specialized PTCA Units with or without Emergency thrombolysis) (24) and WEST (Which Early ST-elevation myocardial infarction Therapy) (25) because they were primarily facilitated PCI trials and the former two trials compared facilitated PCI versus primary PCI.…”

Section: Methodsmentioning

confidence: 99%

Thrombolysis in the Age of Primary Percutaneous Coronary Intervention : Mini-Review and Meta-Analysis of Early PCI

Shammeri¹,

Garcia²

2013

IJHS

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Abstract:Objective: Primary Percutaneous Coronary Intervention (PCI) is the treatment of choice for ST-segment Elevation Myocardial Infarction (STEMI) if performed within 90 minutes from first medical contact. However, primary PCI is only available for less than 25% of patients with STEMI. Early PCI or Pharmaco-invasive strategy has evolved from facilitated PCI but with more delayed timing from thrombolysis to PCI. Aim:Assess the safety and effectiveness of Early PCI. Patients and Method:We reviewed the data of the available therapy options for patients with STEMI. Then we performed a meta-analysis for all randomized controlled trials of early PCI versus standard therapy Results: Five studies fulfilled our inclusion criteria. Our meta-analysis showed improved cardiovascular events with early PCI compared to standard therapy (odd ratio of 0.54; 95% Confidence interval 0.47-0.7, p<0.001). There were no significant bleeding complications when doing early PCI 4 to 24 hours after successful thrombolysis Conclusion: Early PCI should be done to all STEMI patients within 24 hours after successful thrombolysis.

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“…Diese Strategie schließt die frühe Verlegung zur Angiographie und, wenn nö-tig, PCI nach Fibrinolyse ein. Daten aus 7 RCTs mit 2355 Patienten [138,146,[154][155][156][157][158] ergaben Vorteile bezüglich weniger Reinfarkte bei früher regelhafter Verlegung zur Angiographie nach 3−6 h (bis zu 24 h) in den ersten 24 h nach Fibrinolyse im Vergleich zur reinen Verlegung auf die Rescue-PCI nach Fibrinolyse im Krankenhaus (OR 0,57; 95 %-CI 0,38-0,85). Es ergaben sich keine Vorteile bezüglich der kurzzeitigen und Einjahressterblichkeit bzw.…”

Section: Die Kombination Von Fibrinolyse Und Perkutaner Koronarintervunclassified

Das initiale Management des akuten Koronarsyndroms

Νικολάου

Arntz

Bellou

et al. 2015

Notfall Rettungsmed

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Efficacy and Safety of Immediate Angioplasty Versus Ischemia-Guided Management After Thrombolysis in Acute Myocardial Infarction in Areas With Very Long Transfer Distances

Cited by 228 publications

References 29 publications

Treatment of acute myocardial infarction in the sub-arctic region of Norway. Do we offer an equal quality of care?

Treatment of acute myocardial infarction in the sub-arctic region of Norway. Do we offer an equal quality of care?

Thrombolysis in the Age of Primary Percutaneous Coronary Intervention : Mini-Review and Meta-Analysis of Early PCI

Das initiale Management des akuten Koronarsyndroms

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