Efficacy and safety of herbal stimulants and sedatives in sleep disorders

Gyllenhaal, Charlotte; Merritt, Sharon L.; Peterson, Sara Davia; Block, Keith I.; Gochenour, T

doi:10.1053/smrv.1999.0093

Cited by 127 publications

(96 citation statements)

References 53 publications

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“…There have been some reports on the hypnotic effects of these herbal extracts in humans. 4,5) In animal experiments, Soulimani et al 6) also reported that the aqueous extract of passiflora incarnata L caused a decrease of rearing and locomotion in the staircase apparatus or exploratory test. The aqueous extract of passiflora also induced sleep after treatment with a subpharmacological dose of pentobarbital in mice.…”

mentioning

confidence: 99%

Hypnotic Activities of Chamomile and Passiflora Extracts in Sleep-Disturbed Rats

Shinomiya

Inoue²,

Utsu

et al. 2005

Biological & Pharmaceutical Bulletin

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mentioning

confidence: 99%

Hypnotic Activities of Chamomile and Passiflora Extracts in Sleep-Disturbed Rats

Shinomiya

Inoue²,

Utsu

et al. 2005

Biological & Pharmaceutical Bulletin

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“…De los productos naturales que se reportaron en nuestro estudio llama la atención el uso de sustancias naturales con efecto hipnosedante como valeriana o pasiflora que se encuentra en productos como el Soñax Forte®, para el cual, algunos estudios muestran efectividad, es importante considerar el riesgo de interacciones con otros hipnosedantes como medicamentos "Z" (zopiclona entre otros), benzodiacepinas y el potencial riesgo de tolerancia 35,36 . Con respecto al Nux Vómica®, es importante identificarla como un derivado de la estricnina, la cual, al bloquear los receptores de glicina, puede disminuir el umbral convulsivo en personas con esta predisposición 37 .…”

Section: -24unclassified

Actitudes, conocimientos y prácticas frente a la automedicación con productos herbales y psicofármacos en estudiantes de medicina de Medellín-Colombia

Berrouet

Lince

Restrepo

2018

MedUPB

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“…Sedative effects of German chamomile may be due to the benzodiazepine-like compound in the flower head [109].…”

Section: Chamomile (Matricaria Recutita)mentioning

confidence: 99%

Nutritional Modulators of Sleep Disorders

Sarrafi-Zadeh¹

2012

TONUTRAJ

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Abstract:Background: Clinical evidence indicates that insufficient sleep and poor sleep quality appear to be common consequences of shift work. These rhythms appear to have independent influence on the function of the endocrine system, circadian brain function and gastrointestinal tract. Insufficient sleep and its poor quality due to shift work interfere with beta cells, leptin and ghrelin functioning, resulting in factors for the development and exacerbation of insulin resistance. Human studies found that insufficient sleep alters the levels of leptin and ghrelin, two hormones involved in the regulation of appetite and body fat. Leptin, released by fat cells, signals the brain to feel satiety. Ghrelin, produced in the stomach, signals hunger. Investigations reported that temporarily sleep-deprived individuals experienced hormonal changes along with greater cravings for sweet and fatty foods. A further reason for their cravings is related to the stress hormone cortisol, which can rise with sleep deprivation and contribute to hunger. In addition to altered hormone levels, people who stay awake longer have more opportunity to eat, and late-night eating often includes high-caloric foods. Weight gain is only one of the many side effects of insufficient sleep, but it can lead to long-term health problems, including diabetes. Although more sleep will not automatically result in weight loss, sufficient sleep and a regular sleep schedule are critical in controlling appetite and promoting a healthy eating pattern. Research on sleep and appetite reveals a consistent link between a lower amount of sleep and a higher body mass index (BMI), a ratio of weight-to-height that indicates overweight. Studies showed those who slept less than eight hours a night were more likely to be overweight. Methods: Internet search and discussion with colleagues.Results: Recent research indicates that disruption of sleep can influence food intake and food and nutrients can influence sleep. There is evidence that high protein and carbohydrates meals can influence moods, attention and concentration among normal adult subjects with respect to age, gender and meal time. Women reported greater sleepiness after two hours of carbohydrate meal as opposed to a protein meal. On the other hand men reported greater calmness after a carbohydrate as opposed to a protein meal. Age of subjects may also influence the response to meals. After a carbohydrate or protein rich breakfast, persons older than 40 years felt more tense and less calm with a protein-rich than carbohydraterich meal. In general older subjects preferred carbohydrate than protein meals. Carbohydrate meals are also reported to impair objective performance; carbohydrate rich foods either in breakfast or lunch have exhibited negative influence on neural response such as impaired objective performance and poor sustained attention. A meal consumed close to bedtime is associated with sleep disturbances. Further, solid foods as well as large meals may cause more sleepiness than liquid foods. Studies...

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Efficacy and safety of herbal stimulants and sedatives in sleep disorders

Cited by 127 publications

References 53 publications

Hypnotic Activities of Chamomile and Passiflora Extracts in Sleep-Disturbed Rats

Hypnotic Activities of Chamomile and Passiflora Extracts in Sleep-Disturbed Rats

Actitudes, conocimientos y prácticas frente a la automedicación con productos herbales y psicofármacos en estudiantes de medicina de Medellín-Colombia

Nutritional Modulators of Sleep Disorders

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