Efficacy and safety of Chinese herbal medicine in the treatment of Alzheimer's disease: a systematic review and IPD meta-analysis

Abstract

Review question / Objective: This review is intended to explore the efficacy and safety of Chinese Herbal Medicine in the treatment of Alzheimer's disease in comparison with conventional treatment, such as donepezil. Condition being studied: Alzheimer's d i s e a s e ( A D ) i s a p r o g r e s s i v e neurodegenerative disease characterized by the accumulation of amyloid beta in the INPLASY 1

Safety and efficacy of acetylcholinesterase inhibitors for Alzheimer’s disease: A systematic review and meta-analysis

“…Meta-analyses of other treatments, such as like glucagon-like peptide-1 receptor agonists and negative allosteric modulators of 5-hydroxytryptamine 2A receptors, were also conducted by the researchers across the globe. 75,76 Our meta-analysis showed that all 3 acetylcholinesterase inhibitors now in use, i.e., donepezil, galantamine and galantamine, significantly enhance patients' cognitive abilities. However, given to the substantial heterogeneity among the included trials, caution should be exercised in interpreting the results of galantamine and rivastigmine.…”