Efficacy and Safety of Apple Cider Vinegar in the treatment of Molluscum Contagiosum: a Randomized Placebo- Controlled Trial

Abstract

Introduction: Molluscum Contagiosum is a common pox viridae infection among children. Although the condition is benign and self-limiting, treatment is warranted to prevent spread through auto-inoculation or close physical contact. To date no single treatment modality has been proven effective. Apple Cider Vinegar may be an alternative therapeutic option which can be used at home that is non-painful and effective. Objectives: To determine the efficacy and safety of Apple Cider Vinegar in the treatment of Molluscum Contagiosum Methods: The study is a randomized controlled clinical trial that was conducted at the Department of Dermatology of Ospital ng Maynila Medical Center using two types of topical treatment. Fourteen patients aged 2 to 18 who were clinically diagnosed with Molluscum Contagiosum were randomly allocated using sealed paper to apply Apple Cider Vinegar (n=8) or placebo (n=6) on the lesions twice daily for 6 weeks. The patients were blinded to the treatment allocation. Clinical parameters of resolution where noted at weeks 2, 4 and 6. Results: Demographic characteristics showed no statistical difference (p > 0.05). The comparison of apple cider vinegar with the control group did not give any significant difference in resolution of lesions between the two groups at any time point. Erythema was noted by the experimental group which was statistically significant (p = 0.04) Discussion: Apple cider showed promising results when half of the patients in the group showed inflammatory changes, with some of the lesions disappearing by the 4th and 6th week of administration. However, there was no statistical difference in the resolution of the lesions when compared to the placebo group.