Efficacy and possible mechanisms of perillaldehyde in control of Aspergillus niger causing grape decay

Antifungal activity of essential oil from the fruits of Ammodaucus leucotrichus Coss. and Dur., in liquid and vapour phase against postharvest phytopathogenic fungi in apples

“…Perillaldehyde showed also, notable antifungal activity against A. niger, a known cause of grape spoilage, with a minimum inhibitory concentration (MIC) and a minimum fungicidal concentration (MFC) of 0.25 and 1μl/ml, respectively. The accumulation of mycelial biomass was also inhibited by perillaldehyde in a dose-dependent manner, completely inhibiting mycelial growth at 1μl/ml (Tian et al, 2015b). These authors reported that the lipophilic nature of perillaldehyde interacts with the cell membrane of A. niger as a first step in its antifungal activity.…”

“…These authors reported that the lipophilic nature of perillaldehyde interacts with the cell membrane of A. niger as a first step in its antifungal activity. The electrical conductivity in the cell suspensions increased above that of the control at all times when perillaldehyde was added, indicating that the permeability of the cell membrane was compromised (Tian et al, 2015b).When perillaldehyde accumulates at the cytoplasmic membrane, changes in the membrane integrity occur, such as expansion (swelling) of the membrane, which may result in a destabilization of the membrane and subsequent ion leakage (Ultee et al, 2002). Another assumption is that perillaldehyde probably acted as a signal that triggered the transcription processes of some specific "fungicidal" genes in the fruits (Panahirad et al, 2012).…”

Induced cell death in Ceratocystis fimbriata by pro‐apoptotic activity of a natural organic compound, perillaldehyde, through Ca2+ overload and accumulation of reactive oxygen species

“…In the past, synthetic fungicides were widely used to control these pathogens, but current use restrictions of synthetic fungicides have created a need for safer alternatives, such as natural preservatives. The application of essential oils has recently become a very attractive method of controlling fungal pathogens (Tian et al ., ). The present study further demonstrates that PAE can be used as a natural preservative for controlling postharvest rot of root crops.…”

“…PAE exhibits antioxidant, antidepressant and other biological properties (Ito et al ., ; Jin et al ., ). PAE has been evaluated as a natural preservative for controlling fungal pathogens in sweet potato (Zhang et al ., ), table grapes and cherry tomatoes (Tian et al ., ,). It also shows antifungal activity against Aspergillus flavus , Aspergillus niger , Candida albicans and other microbes (McGeady et al ., ; Tian et al ., ).…”

Wine Contamination with Ochratoxins: A Review

“…Some natural fungicides have been tested in vitro against black Aspergilli isolated from grapes. Perillaldehyde and natamycin showed antifungal activity in vitro and reduced OTA production by black Aspergilli, but their effectiveness has not been tested on grapes yet [120,121]. Favilla et al [122] tested the effectiveness of fusopyrone on artificially contaminated grapes in highly conductive conditions to mold development and observed an almost complete inhibition of growth and a drastic reduction on OTA content of grapes.…”