Efficacy and economic benefits of a modified Valsalva maneuver in patients with paroxysmal supraventricular tachycardia

Efficacy and safety of modified Valsalva maneuver for treatment of paroxysmal supraventricular tachycardia: a meta-analysis

“…Two studies 14,15 contained insufficient information regarding sequence generation. Furthermore, most included studies 3,4,7,8,[11][12][13][14][15][16][17][18][19][22][23][24] lacked information about allocation concealment.…”

“…Furthermore, most included studies 3,4,7,8,[11][12][13][14][15][16][17][18][19][22][23][24] lacked information about allocation concealment. The majority of the evaluated trials 3,4,7,8,[11][12][13][14][15][17][18][19][21][22][23][24] had an unclear risk of bias in terms of participant, personnel, and outcome assessor blinding. However, all included trials had a low risk of bias in terms of selective outcome reporting and incomplete outcome data.…”

“…In total, 228 records were identified from the various databases examined, and 18 records were identified from citation searching. After a detailed assessment based on the inclusion criteria, 19 studies 3,4,[6][7][8][11][12][13][14][15][16][17][18][19][20][21][22][23][24] involving 2527 patients with PSVT were included in the meta-analysis (Figure 1). All studies were published from 2015 to 2022.…”

“…All studies 3,4,[6][7][8][11][12][13][14][15][16][17][18][19][20][21][22][23][24] reported the overall rate of cardioversion, including that associated with single and multiple Valsalva maneuvers, and 12 studies 3,4,7,[11][12][13][15][16][17][18][19]24 reported the rate of cardioversion after a single Valsalva maneuver. Eight studies 4,7,11,13,15,20,22,24 repeated the standard or modified Valsalva maneuver up to two times if sinus rhythm was not restored after the first attempt, three studies 6,16,21 repeated the maneuver up to three times, two studies 17,18 repeated the maneuver up to five times, and six studies 3,8,12,14,…”

“…Two studies 14,15 contained insufficient information regarding sequence generation. Furthermore, most included studies 3,4,7,8,[11][12][13][14][15][16][17][18][19][22][23][24] lacked information about allocation concealment. The majority of the evaluated trials 3,4,7,8,[11][12][13][14][15][17][18][19][21][22][23][24] had an unclear risk of bias in terms of participant, personnel, and outcome assessor blinding.…”