Effets des solutés de remplissage vasculaire sur l’hémostase

Blanlœil, Y.; Trossaërt, Marc; Rigal, Jean-Christophe; Rozec, Bertrand

doi:10.1016/s0750-7658(02)00695-0

Cited by 17 publications

(5 citation statements)

References 129 publications

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“…Several studies on the effect of colloids (including various artificial colloids and albumin) on coagulation have indicated that artificial colloids may inhibit platelet function, decrease von Willebrand Factor (vWF) and factor VIII activity, and induce hypocoagulation and fibrin polymerization. However, albumin was not found to play significant roles in these phenomena [36,37] . This may be a potential advantage of albumin over artificial colloids for fluid resuscitation in patients with hemorrhagic shock, but this advantage has not yet been demonstrated in RCTs.…”

Section: Recommendations For the Use Of Hsa In Patients With Hemorrha...mentioning

confidence: 97%

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Expert consensus on the use of human serum albumin in critically ill patients

Liu

et al. 2021

Chinese Medical Journal

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Section: Recommendations For the Use Of Hsa In Patients With Hemorrha...mentioning

confidence: 97%

“…However, albumin was not found to play significant roles in these phenomena. [36,37] This may be a potential advantage of albumin over artificial colloids for fluid resuscitation in patients with hemorrhagic shock, but this advantage has not yet been demonstrated in RCTs.…”

Section: Development Process Of the Consensusmentioning

confidence: 99%

Expert consensus on the use of human serum albumin in critically ill patients

Liu

et al. 2021

Chinese Medical Journal

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“…The systemic in ammatory response syndrome (SIRS) caused by the release of a high number of pro-in ammatory cytokines leads to vascular system damage and extensive microthrombosis [24][25][26] . Moreover, some pro-in ammatory factors such as IL-6 and TNF-α inhibit the synthesis of albumin in the liver 27-29 . Albumin is involved in the regulation of coagulation function, and hypoproteinemia can lead to hypercoagulability 30 . In our study, the use of antibiotics resulted in a decrease in albumin and an increase in D-dimer, which indicated that increased release of pro-in ammatory factors caused by antibiotics may exacerbate hypoproteinemia and secondary brinolysis hyperactivity.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of early antibiotics use in non-severe COVID-19 patients admitted with low risk of bacterial infection

Yin

Liu

et al. 2020

Preprint

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Abstract The use of antibiotics is common in the treatment of COVID-19, but adequate evaluation is lacking. This study aimed to evaluate the effect of early antibiotic use in non-severe COVID-19 patients admitted with low risk of bacterial infection. The multi-center retrospective cohort study included 1613 non-severe COVID-19 inpatients admitted with low risk of bacterial infection. During the follow-up of 30 days, the proportion of patients progressed into severe type COVID-19 in the early antibiotics use group was almost 1.5 times than that of the comparision group. In the mixed-effect model, the early use of antibiotics was associated with higher probability of developing severe type, staying in the hospital for over 15 days, and secondary infection. However, it was not significant association with mortality rate. Analysis with propensity score-matched cohort displayed similar results. It is suggested that antibiotic use should be avoided unless absolutely necessary in non-severe COVID-19 patients, particularly in the early stages.

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“…Therefore, the mention of clinical and therapeutic information on patient prescription cards is essential. This allows the biologist to correctly interpret the results obtained, and also to act by carrying out, if necessary, additional examinations that can provide more details for the diagnosis [1,4,[13][14][15][16]. In the series of Tadesse et al [6], clinical and therapeutic information was on prescription cards in 70.1% of cases.…”

Section: Discussionmentioning

confidence: 99%

“…The rate of under-filling tubes from services (28%) was higher than that of tubes received from the blood drawing room (19%). Our rates are high by comparing them to the rates of similar studies [5][6][7][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25].…”

Section: Discussionmentioning

confidence: 99%

Pre-analytical Phase in Hemostasis: The Main Anomalies and Means to Correct Them

Siham¹,

Ikhlas²,

Raihane³

et al. 2019

AJLM

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Pre-analytical errors still represent nearly 70% of all errors occurring in the laboratory, constituting a danger, a waste of time and an additional cost to the patient. The control of the different components of the pre-analytical step is important for the validity of the hemostasis exploration tests. The purpose of our work is to identify the main anomalies of the pre-analytical phase in hemostasis and to propose the means to correct them. We conducted a prospective and descriptive study on the pre-analytical phase of hemostasis. It was in the form of a survey, identifying the main errors related to this phase. It was performed at the Hematology laboratory of the Avicenna Military Hospital of Marrakech and spread over a period of 4 weeks. Our investigation took place at the hemostasis room, which received the collection tubes from the various hospital departments and the blood drawing room (for non-hospitalized patients). The hemostasis room received 400 prescription cards and their corresponding tubes. The parameters related to the prescription file: full name and gender of the patients, were mentioned on all the cards received and they were in conformity with those marked on the corresponding tube. The age of the patients and their clinical and therapeutic informations were mentioned in 73% and 13% of the exam requests, respectively. For the pre-analytical hemostasis parameters related to the blood collection: 63% of samples were taken at the laboratory's blood drawing room, while 37% came from the various hospital departments. Time of the realization of the samples was not mentioned on the cards or on the labels of the tubes. The anticoagulant used for all samples was sodium citrate at a concentration of 3.8%. The filling of the tubes was noncompliant in 22.25%. Registration and triage of the tubes systems were manual. Centrifugation was carried out at a rotation speed of 5000 G for 5 minutes and at a temperature set at 22°C. Hemolyzed samples accounted for 3% of the tubes.

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Effets des solutés de remplissage vasculaire sur l’hémostase

Cited by 17 publications

References 129 publications

Expert consensus on the use of human serum albumin in critically ill patients

Expert consensus on the use of human serum albumin in critically ill patients

Evaluation of early antibiotics use in non-severe COVID-19 patients admitted with low risk of bacterial infection

Pre-analytical Phase in Hemostasis: The Main Anomalies and Means to Correct Them

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