Effet de l’extrait aqueux de l’écorce de tige de &lt;i&gt;Anthocleista djalonensis&lt;/i&gt; A. Chev (Gentianaceae) sur la glycémie des lapins

Kroa, Ehoulé; Doh, Stéphane Koffi; Soko, Yves Niabith; Yohou, Kévin Sylvestre; Koulaï, Omer Jean-Jacques Déassio; Gbogbo, Moussa; N'Guessan, K.F.; Aka, Joseph; Kouassi, Dinard

doi:10.4314/ijbcs.v10i2.9

Cited by 4 publications

(5 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The sharp decrease in blood glucose is closer to that obtained with the extracts of Anthocleista djalonensis and Bidens pilosa. Indeed, Kroa et al (2016) reported the hypoglycaemic properties of the aqueous extract of stem bark of Anthocleista djalonensis at a concentration of 2500 mg / kg body weight in treated rabbits. With the aqueous extract of Bidens pilosa, a better reduction of blood sugar is obtained.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Hypoglycemic Potential of Aqueous Extracts of Ageratum Conyzoides L., Anthocleista Djalonensis A. Chev. and Bidens Pilosa L., Three Plants from the Ivorian Pharmacopoeia

Gnagne

Coulibaly

Fofie

et al. 2018

ESJ

View full text Add to dashboard Cite

Ageratum conyzoides L. (Asteraceae), Anthocleista djalonensis A. Chev. (Gentianaceae) and Bidens pilosa L. (Asteraceae) are three plants used in traditional medicine to treat diabetes. The objective of this present study was to investigate the hypoglycemic potential of the aqueous extracts of these three plants, in order to justify their use by traditional healers. Each extract and both control substances were administered at a single dose to animals by gavage using a catheter for each concentration (70, 90 and 110 mg / ml), at the recommended dose (2 ml / 100g of b.w). The search for the hypoglycemic effect of the aqueous extract of each plant in normal glycemic rats given orally showed a decrease in blood glucose. The aqueous extract of Bidens pilosa induces a significant dose-dependent hypoglycaemia. The phytochemical study has revealed the presence of polyphenols, flavonoids, tannins (catechins and gallic), saponosides and alkaloids, compounds with multiple medical properties, including glycemic regulation in diabetics. The study revealed that the aqueous extracts of the three plants have a hypoglycemic potential with the aqueous extract of Bidens pilosa showing better activity, the results of our investigation justify their use in traditional medicine in the treatment of diabetes.

show abstract

Section: Discussionmentioning

confidence: 99%

“…In Côte d'Ivoire, the International Diabetes Federation (IDF) estimated in 2014 the prevalence of diabetes mellitus at 9.6%, which is a major public health problem (Kroa et al, 2016). The therapeutic management of diabetes is currently based on strict dieting and the use of oral antidiabetic drugs.…”

Section: Introductionmentioning

confidence: 99%

Hypoglycemic Potential of Aqueous Extracts of Ageratum Conyzoides L., Anthocleista Djalonensis A. Chev. and Bidens Pilosa L., Three Plants from the Ivorian Pharmacopoeia

Gnagne

Coulibaly

Fofie

et al. 2018

ESJ

View full text Add to dashboard Cite

show abstract

“…D'ici à 2035, ces estimations devraient doubler et atteindre 41,5 millions, soit une augmentation de 109% (SANOFI, 2014). Pour la Côte d'Ivoire, la Fédération Internationale du Diabète (FID) a estimé en 2014, la prévalence du diabète sucré à 9,6%, ce qui est un problème majeur de santé publique (Kroa et al, 2016). Le diabète et ses complications ont des répercussions socioéconomiques importantes.…”

Section: Introductionunclassified

Étude ethnobotanique des plantes médicinales utilisées dans le traitement du diabète dans le Département de Zouénoula (Côte d’Ivoire)

Gnagne¹,

Camara²,

Fofie³

et al. 2017

J. App. Bioscience.

View full text Add to dashboard Cite

Objective: The aim of this study is to contribute to a better knowledge of medicinal antidiabetic herbs used in the Zouénoula Department. Methodology and results: Ethnobotanical surveys were carried out using questionnaires from the Department's healers. The results obtained made it possible to inventory seventeen species of medicinal plants belonging to fourteen botanical families and divided into sixteen genera. Among these species, Ageratum conyzoides (Goatweed), Anthocleista djalonensis (Cabbage tree) and Bidens pilosa (Black jack) are the most recommended. The leaves are the most used organs. The decoction is the mode of preparation most requested and the administration is done mainly by oral way. Conclusion and application of results:This work constitutes a source of information which can serve as a basis for pharmacological studies in order to evaluate the therapeutic efficacy and safety of these three plants with traditional antidiabetic effect.

show abstract

“…In addition, various scientific studies have confirmed the exceptional medicinal virtues of this plant. In such a study, the hypoglycemic effect of the aqueous stem bark extract of A. djalonensis was established by the oral route in normoglycemic and hyperglycemic rabbits (Kroa et al, 2016). Besides, in vitro antiplasmodial assay revealed that the aqueous and ethanol extracts of this plant to inhibit growth of clinical isolates and chloroquinoresistant strains (K1).…”

Section: Introductionmentioning

confidence: 99%

Chemical characterization and biological abilities of Anthocleista djalonensis collected from two locations of Ivory Coast

Sinan

Zengin

Uba³

et al. 2023

eFood

View full text Add to dashboard Cite

In this study, the total phenolic and flavonoid contents, HPLC‐DAD detected phytochemicals, antioxidant and enzyme inhibitory potential of methanolic and aqueous (as infusion) extracts of the medicinal plant, Anthocleista djalonensis (leaf and stem bark) collected from two locations, Mafiblé and Prikro, in Ivory Coast, were investigated. The ranges of total phenolic and flavonoid contents obtained were 14.17–46.95 mg gallic acid equivalent (GAE)/g and 2.96–34.76 mg rutin equivalent (RE)/g, respectively. Antioxidant abilities in terms of radical scavenging, reducing and metal chelating activity of the extracts in different assays were as follows: DPPH (4.90–48.82 mg trolox equivalent [TE]/g), ABTS (21.05–81.89 mg TE/g), CUPRAC (29.54–122.33 mg TE/g), FRAP (17.53–94.06 mg TE/g) and metal chelating (10.09–28.49 mg EDTAE/g. The extracts of A. djalonensis collected from Mafiblé, especially those of stem bark, contained higher level of total bioactive contents compared to Prikro extracts, detected by high‐performance liquid chromatography with photodiode‐array detection (HPLC‐DAD). Only the methanolic extracts irrespective of plant parts/location, showed inhibition against acetylcholinesterase (1.42–2.12 mg galantamine equivalent (GALAE)/g), while only the stem bark methanolic extract of A. djalonensis from Mafiblé was found to inhibit butyrylcholinesterase (0.65 mg GALAE/g). Thus, findings from this study could be useful for better application of the medicinal benefits from this plant.

show abstract

Effet de l’extrait aqueux de l’écorce de tige de <i>Anthocleista djalonensis</i> A. Chev (Gentianaceae) sur la glycémie des lapins

Cited by 4 publications

References 2 publications

Hypoglycemic Potential of Aqueous Extracts of Ageratum Conyzoides L., Anthocleista Djalonensis A. Chev. and Bidens Pilosa L., Three Plants from the Ivorian Pharmacopoeia

Hypoglycemic Potential of Aqueous Extracts of Ageratum Conyzoides L., Anthocleista Djalonensis A. Chev. and Bidens Pilosa L., Three Plants from the Ivorian Pharmacopoeia

Étude ethnobotanique des plantes médicinales utilisées dans le traitement du diabète dans le Département de Zouénoula (Côte d’Ivoire)

Chemical characterization and biological abilities of Anthocleista djalonensis collected from two locations of Ivory Coast

Contact Info

Product

Resources

About